Remember Me
Or use your Academic/Social account:


Or use your Academic/Social account:


You have just completed your registration at OpenAire.

Before you can login to the site, you will need to activate your account. An e-mail will be sent to you with the proper instructions.


Please note that this site is currently undergoing Beta testing.
Any new content you create is not guaranteed to be present to the final version of the site upon release.

Thank you for your patience,
OpenAire Dev Team.

Close This Message


Verify Password:
Verify E-mail:
*All Fields Are Required.
Please Verify You Are Human:
fbtwitterlinkedinvimeoflicker grey 14rssslideshare1
Santodomingo-Rubido, Jacinto; Villa-Collar, César; Gilmartin, Bernard; Gutiérrez-Ortega, Ramón; Suzaki, Asaki
Languages: English
Types: Article
Subjects: Ortoqueratología, Visión - Trastornos, Óptica, Optometría, Vista, Miopía progresiva

Classified by OpenAIRE into

mesheuropmc: sense organs, genetic structures, eye diseases
The aim was to assess the potential association between entrance pupil location relative to the coaxially sighted corneal light reflex (CSCLR) and the progression of myopia in children fitted with orthokeratology (OK) contact lenses. Additionally, whether coma aberration induced by decentration of the entrance pupil centre relative to the CSCLR, as well as following OK treatment, is correlated with the progression of myopia, was also investigated.Twenty-nine subjects aged six to 12 years and with myopia of -0.75 to -4.00 DS and astigmatism up to 1.00 DC were fitted with OK contact lenses. Measurements of axial length and corneal topography were taken at six-month intervals over a two-year period. Additionally, baseline and three-month topographic outputs were taken as representative of the pre- and post-orthokeratology treatment status. Pupil centration relative to the CSCLR and magnitude of associated corneal coma were derived from corneal topographic data at baseline and after three months of lens wear.The centre of the entrance pupil was located superio-temporally to the CSCLR both pre- (0.09 ± 0.14 and -0.10 ± 0.15 mm, respectively) and post-orthokeratology (0.12 ± 0.18 and -0.09 ± 0.15 mm, respectively) (p > 0.05). Entrance pupil location pre- and post-orthokeratology lens wear was not significantly associated with the two-year change in axial length (p > 0.05). Significantly greater coma was found at the entrance pupil centre compared with CSCLR both pre- and post-orthokeratology lens wear (both p < 0.05). A significant increase in vertical coma was found with OK lens wear compared to baseline (p < 0.001) but total root mean square (RMS) coma was not associated with the change in axial length (all p > 0.05).Entrance pupil location relative to the CSCLR was not significantly affected by either OK lens wear or an increase in axial length. Greater magnitude coma aberrations found at the entrance pupil centre in comparison to the CSCLR might be attributed to centration of orthokeratological treatments at the CSCLR. 1.280 JCR (2015) Q3, 39/56 Ophthalmology UEM
  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

    • 1. Charman WN. Wavefront technology: past, present and future. Contact Lens Ant Eye 2005;28:75-92.
    • 2. Swarbrick HA. Orthokeratology review and update. Clin Exp Optom 2006;89:124-143.
    • 3. Hiraoka T, Mihashi T, Okamoto C, Okamoto F, Hirohara Y, Oshika T. Influence of induced decentered orthokeratology lens on ocular higherorder wavefront aberrations and contrast sensitivity function. J Cataract Refract Surg 2009;35:1918-1926.
    • 4. Swarbrick HA, Wong G, O'Leary DJ. Corneal response to orthokeratology. Optom Vis Sci 1998;75:791-799.
    • 5. Nichols JJ, Marsich MM, Nguyen M, Barr JT, Bullimore MA. Overnight orthokeratology. Optom Vis Sci 2000;77:252-259.
    • 6. Alharbi A, Swarbrick HA. The effects of overnight orthokeratology lens wear on corneal thickness. Invest Ophthalmol Vis Sci 2003;44:2518- 2523.
    • 7. Mandel RB. Apparent pupil displacement in videokeratography. CLAO J 1994;20:123-127.
    • 8. Applegate RA, Thibos LN, Twa MD, Sarver EJ. Importance of fixation, pupil center, and reference axis in ocular wavefront sensing, videokeratography, and retinal image quality. J Cataract Refract Surg 2009;35:139-152.
    • 9. Salmon TO, Thibos LN. Videokeratoscope-line-of-sight misalignment and its effect on measurements of corneal and internal ocular aberrations. J Opt Soc Am A 2002;19:657-669.
    • 11. Walline JJ, Jones LA, Sinnott LT. Corneal reshaping and myopia progression. Br J Ophthalmol 2009;93:1181-1185.
    • 12. Kakita T, Hiraoka T, Oshika T. Influence of overnight orthokeratology on axial length elongation in childhood myopia. Invest Ophthalmol Vis Sci 2011;52:2170-2174.
    • 13. Hiraoka T, Kakita T, Okamoto F, Takahashi H, Oshika T. Long-term effect of overnight orthokeratology on axial length elongation in childhood myopia: a 5-year follow-up study. Invest Ophthalmol Vis Sci 2012;53:3913-3919.
    • 14. Santodomingo-Rubido J, Villa-Collar C, Gilmartin B, Gutiérrez-Ortega R. Myopia control with orthokeratology contact lenses in Spain: refractive and biometric changes. Invest Ophthalmol Vis Sci 2012;53:5060-5065.
    • 15. Cho P, Cheung SW. Retardation of Myopia in Orthokeratology (ROMIO) Study: a 2-year randomized clinical trial. Invest Ophthalmol Vis Sci 2012;53:7077-7085.
    • 16. Smith EL, Kee CS, Ramamirtham R, Qiao-Grider Y, Hung LF. Peripheral vision can influence eye growth and refractive development in infant monkeys. Invest Ophthalmol Vis Sci 2005;46:3965-3972.
    • 17. Smith EL 3rd, Ramamirtham R, Qiao-Grider Y et al. Effects of foveal ablation on emmetropization and form-deprivation myopia. Invest Ophthalmol Vis Sci 2007;48:3914-3922.
    • 18. Queirós A, González-Méijome JM, Jorge J, Villa-Collar C, Gutiérrez AR. Peripheral refraction in myopic patients after orthokeratology. Optom Vis Sci 2010;87:323-329.
    • 19. Lin Z, Martinez A, Chen X et al. Peripheral defocus with single-vision spectacle lenses in myopic children. Optom Vis Sci 2010;87:4-9.
    • 20. Kang P, Swarbrick H. Peripheral refraction in myopic children wearing orthokeratology and gas-permeable lenses. Optom Vis Sci 2011;88:476- 482.
    • 21. Zhong Y, Chen Z, Xue F, Zhou J, Niu L, Zhou X. Corneal power change is predictive of myopia progression in orthokeratology. Optom Vis Sci 2014;91:404-411
    • 22. Hiraoka T, Matsumoto Y, Okamoto F, Yamaguchi T, Hirohara Y, Mihashi T, Oshika T. Corneal higher-order aberrations induced by overnight orthokeratology. Am J Ophthalmol 2005;139:429-436.
    • 23. Hiraoka T, Okamoto C, Ishii Y, Kakita T, Oshika T. Contrast sensitivity function and ocular higher order aberrations following overnight orthokeratology. Invest Ophthalmol Vis Sci 2007;48:550-556.
    • 24. Anera RG, Villa C, Jiménez JR, Gutierrez R. Effect of LASIK and contact lens corneal refractive therapy on higher order aberrations and contrast sensitivity function. J Refract Surg 2009;25(3):277-284.
    • 25. Gifford P, Li M, Lu H, Miu J, Panjaya M, Swarbrick HA. Corneal versus ocular aberrations after overnight orthokeratology. Optom Vis Sci 2013;90:439-447.
    • 26.Lian Y, Shen M, Huang S, Yuan Y, Wang Y, Zhu D, Jiang J, Mao X, Wang J, Lu F. Corneal reshaping and wavefront aberrations during overnight orthokeratology. Eye Contact Lens 2014;40:161-168.
    • 27.Hiraoka T, Kakita T, Okamoto F, Oshika T. Influence of ocular wavefront aberrations on axial length elongation in myopic children treated with overnight orthokeratology. Ophthalmology 2014;15:S0161- 6420.
    • 28.Mahajan VN. Optical imaging and aberrations, I: ray geometrical optics. SPIE 1998;1:438-442.
    • 29.Santodomingo-Rubido J, Villa-Collar C, Gilmartin B, Gutiérrez-Ortéga R. Myopia control with orthokeratology contact lenses in Spain (MCOS): study design and general baseline characteristics. J Optom 2009;2:215-2.
    • 30.Santodomingo-Rubido J, Villa-Collar C, Gilmartin B, Gutiérrez-Ortega R. Orthokeratology vs. Spectacles: Adverse Events and Discontinuations. Optom Vis Sci 2012;89:1133-9.
    • 31.Santodomingo-Rubido J, Villa-Collar C, Gilmartin B, Gutiérrez-Ortega R. Myopia Control with Orthokeratology contact lenses in Spain (MCOS): a comparison of vision-related quality-of-life measures between orthokeratology contact lenses and single-vision spectacles. Eye Contact Lens 2013;39:153-7.
    • 32.Santodomingo-Rubido J, Villa-Collar C, Gilmartin B, Gutiérrez-Ortega R. Factors Preventing Myopia Progression with Orthokeratology Correction. Optom Vis Sci 2013;90:1225-36.
    • 33.Santodomingo-Rubido J, Villa-Collar C, Gilmartin B, Gutiérrez-Ortega R. Short-term changes in ocular biometry and refraction after discontinuation of long-term orthokeratology. Eye Contact Lens 2014;40:84-90.
    • 34.Terry RL, Schnider CM, Holden BA et al. CCLRU standards for successful daily wear and extended wear contact lenses. Optom Vis Sci 1993;70:234-243.
    • 35.Lovie-Kitchin JE, Brown B. Repeatability and intercorrelations of standard vision tests as a function of age. Optom Vis Sci 2000;77:412- 420
    • 36.Santodomingo-Rubido J, Mallen EA, Gilmartin B et al. A new non-contact optical device for ocular biometry. Br J Ophthalmol 2002;86:458-2.
    • 37.Thibos LN, Applegate RA, Schweigerling JT,Webb R. Standards for reporting the optical aberrations of the eye. J Refract Surg 2002;18:652- 60.
    • 38.ANSI American National Standards. American National Standard for Ophthalmics-methods for reporting optical aberrations of eyes. ANSI Z80.28; 2004.
    • 39.Barbero S, Marcos S, Merayo-Lloves JM, Moreno- Barriuso E. Validation of the estimation of corneal aberrations from videokeratography: a test on keratoconus eyes. J Refract Surg 2002;18:263-270.
    • 40.Kosaki R, Maeda N, Bessho K et al. Magnitude and orientation of Zernike terms in patients with keratoconus. Invest Ophthalmol Vis Sci 2007;48:3062-3068.
    • 41.Thibos LN, Wheeler W, Horner D. Power vectors: an application of Fourier analysis to the description and statistical analysis of refractive error. Optom Vis Sci 1997;74:367-75.
    • 42.Yang Y, Thompson K, Burns SA. Pupil location under mesopic, photopic, and pharmacologically dilated conditions. Invest Ophthalmol Vis Sci 2002;43:2508-2512.
    • 43.Tabernero J, Atchison DA, Markwell EL. Aberrations and pupil location under corneal topography and Hartmann-Shack illumination conditions. Invest Ophthalmol Vis Sci 2009;50:1964-1970.
    • 44.Basmak H, Sahin A, Yildirim N, Papakostas TD, Kanellopoulos AJ. Measurement of angle kappa with synoptophore and Orbscan II in a normal population. J Refract Surg 2007;23:456-460.
    • 45.Bueeler M, Mrochen M, Seiler T. Maximum permissible lateral decentration in aberration-sensing and wavefront-guided corneal ablation. J Cataract Refract Surg 2003;29:257-263.
    • 46.Reinstein DZ, Gobbe M, Archer TJ. Coaxially sighted corneal light reflex versus entrance pupil center centration of moderate to high hyperopic corneal ablations in eyes with small and large angle kappa. J Refract Surg 2013;29:518-525.
    • 47.Charman WN. Aberrations and myopia. Ophthal Physiol Opt 2005;25:285-301.
    • 48.Marcos S, Barbero S, Llorente L. The sources of optical aberrations in myopic eyes. Invest Ophthalmol Vis Sci 2002; 43(suppl.): Abstract 1510.
    • 49.Artal P, Guirao A, Berrio E, Williams DR. Compensation of corneal aberrations by the internal optics in the human eye. J Vis 2001;1: 1-18.
    • 50.Philip K, Sankaridurg P, Holden B, Ho A, Mitchell P. Influence of higher order aberrations and retinal image quality in myopisation of emmetropic eyes. Vision Res 2014;105:233-43.
  • No related research data.
  • Discovered through pilot similarity algorithms. Send us your feedback.

Share - Bookmark

Cite this article