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Lord, R; George, KP; Somauroo, J; Stembridge, M; Jain, N; Hoffman, MD; Shave, R; Haddad, F; Ashley, E; Jones, H; Oxborough, D
Publisher: Elsevier
Languages: English
Types: Article
Subjects: RC1200
BACKGROUND: The aim of this study was to use novel area-deformation (ε) loops to interrogate the interaction between the right ventricular (RV) and left ventricular (LV) mechanics following a 100-mile endurance run. METHODS: Fifteen participants (mean body mass, 70.1 ± 8.8 kg; mean age, 40 ± 8 years) were recruited for the study. Echocardiography was performed before the race, after the race, and 6 hours into recovery. RV and LV area and longitudinal ε were assessed using standard and speckle-tracking echocardiography. Following cubic spline interpolation, these variables were obtained across the same cardiac cycle and used to derive area-ε loops. RESULTS: The RV area-ε loop demonstrated a rightward shift after the race, with increased RV area (from 26.0 to 27.1 cm(2)) and reduced peak RV ε (from -28.6% to -25.8%). The recovery RV area-ε loop was similar to the postrace loop. A leftward shift was observed in the LV area-ε loop after the race, secondary to reduced LV area (from 35.8 to 32.5 cm(2)) and reduced peak ε (from -18.3% to -16.6%). In recovery, LV ε values returned toward baseline. CONCLUSIONS: A 100-mile ultramarathon resulted in a rightward shift in the RV area-ε loop as a result of RV dilatation. There was a concomitant leftward shift in the LV area-ε loop as a result of underfilling of the left ventricle. At 6 hours after exercise, there was a partial recovery of the left ventricle, while RV function remained depressed. It appears that changes in RV function do not have a serial impact on the left ventricle during recovery from ultra-endurance activity.
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    • 23. Burns AT, La Gerche A, Prior DL, Macisaac AI. Left ventricular torsion parameters are affected by acute changes in load. Echocardiogr. 2010;27(4):407-14. RA VOL ES (ml) 62 ± 23 62 ± 14 58 ± 22 RA VOL pre A (ml) 42 ± 14 46 ± 13 40 ± 13 RA VOL ED (ml) 28 ± 9 29 ± 11 27 ± 8 RA RES (ml) 34 ± 15 33 ± 9 31 ± 15 RA BOO (ml) 14 ± 7 17 ± 8 14 ± 7 *indicates statistical significance pre to post race (P<0.01). Data analysed using paired t-tests and presented as mean±SD
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