Remember Me
Or use your Academic/Social account:


Or use your Academic/Social account:


You have just completed your registration at OpenAire.

Before you can login to the site, you will need to activate your account. An e-mail will be sent to you with the proper instructions.


Please note that this site is currently undergoing Beta testing.
Any new content you create is not guaranteed to be present to the final version of the site upon release.

Thank you for your patience,
OpenAire Dev Team.

Close This Message


Verify Password:
Verify E-mail:
*All Fields Are Required.
Please Verify You Are Human:
fbtwitterlinkedinvimeoflicker grey 14rssslideshare1
Phillips, Justin P.; Hickey, Michelle; Kyriacou, Panayiotis A. (2012)
Publisher: Molecular Diversity Preservation International (MDPI)
Journal: Sensors (Basel, Switzerland)
Languages: English
Types: Article
Subjects: capacitance, noninvasive, TP1-1185, TK, Chemical technology, plethysmography, hemoglobin, Article

Classified by OpenAIRE into

mesheuropmc: sense organs
Completely noninvasive monitoring of hemoglobin concentration has not yet been fully realized in the clinical setting. This study investigates the viability of measuring hemoglobin concentration noninvasively by evaluating the performance of two types of sensor using a tissue phantom perfused with a blood substitute. An electrical sensor designed to measure blood volume changes during the cardiac cycle was used together with an infrared optical sensor for detection of erythrocyte-bound hemoglobin. Both sensors demonstrated sensitivity to changes in pulse volume (plethysmography). The electrical sensor produced a signal referred to as capacitance plethysmograph (CPG) a quantity which was invariant to the concentration of an infrared absorbing dye present in the blood substitute. The optical sensor signal (photoplethysmograph) increased in amplitude with increasing absorber concentration. The ratio PPG:CPG is invariant to pulse pressure. This quantity is discussed as a possible index of in vivo hemoglobin concentration.
  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

    • 1. Preventing Micronutrient Deficiencies; ICN Fact Sheet Number One; FAO/WHO: Rome, Italy, 1992.
    • 2. Indicators and Strategies for Iron Deficiency and Anemia Programmes; Report of the WHO/UNICEF/UNU Consultation; WHO: Geneva, Switzerland, 1993.
    • 3. Prakash, S.; Kapil, U.; Singh, G.; Dwivedi, S.N. Tandon, M. Utility of HemoCue in Estimation of Hemoglobin against Standard Blood Cell Counter Method. J. Assoc. Phys. India 1999, 47, 995-997.
    • 4. Richards, N.A.; Boyce, H.; Yentis, S.M. Estimation of Blood Hemoglobin Concentration Using the HemoCue during Caesarean Section: The Effect of Sampling Site. Int. J. Obstet. Anesth. 2010, 19, 67-70.
    • 5. Barker, S.J.; Badal, J.J. The Measurement of Dyshemoglobins and Total Hemoglobin by Pulse Oximetry. Curr. Opin. Anasthesiol. 2008, 21, 805-810.
    • 6. Macknet, M.R.; Allard, M.; Applegate, R.L., 2nd; Rook, J. The Accuracy of Noninvasive and Continuous Total Hemoglobin Measurement by Pulse CO-Oximetry in Human Subjects Undergoing Hemodilution. Anesth. Analg. 2010, 111, 1424-1426.
    • 7. Nyboer, J.; Kreider, M.M.; Hannapel, L. Electrical Impedance Plethysmography: A Physical and Physiologic Approach to Peripheral Vascular Study. Circulation 1950, 2, 811-821.
    • 8. Santic, A.; Stritof, T.; Bilas, V. Plethysmography Measurements Using Short Current Pulses with Low Duty Cycle. In Proceedings of the 20th IEEE EMBC Annual International Conference, Hong Kong, China, 29 October-1 November 1998.
    • 9. Nyboer, J. Electrical Impedance Plethysmography: The Electrical Resistive Measure of the Blood Pulse Volume, Peripheral and Central Blood Flow; Thomas: Springfield, IL, USA, 1959.
    • 10. Ravi Shankar, T.M.; Webster, J.G.; Shao, S. The Contribution of Vessel Volume Change and Blood Resistivity Change to the Electrical Impedance Pulse. IEEE Trans. Biomed. Eng. 1985, BME-32, 192-198.
    • 11. Wood, J.R.; Hyman, C. A Direct Reading Capacitance Plethysmograph. Med. Biol. Eng. Comp. 1970, 8, 59-70.
    • 12. Jaspard, F.; Nadi, M.; Rouane, A. Dielectric Properties of Blood: An Investigation of Haematocrit Dependence. Physiol. Meas. 2003, 24, 137-147.
    • 13. Treo, E.F.; Felice, C.J.; Tirado, M.C. Hematocrit Measurement by Dielectric Spectroscopy. IEEE Trans. Biomed. Eng. 2005, 52, 124-127.
    • 14. Phillips, J.P.; Hickey, M.; Kyriacou, P.A. Electro-Optical Plethysmography for Noninvasive Estimation of Hemoglobin Concentration. In Proceedings of the 33rd IEEE EMBC Annual International Conference, Boston, MA, USA, 30 August-3 September 2011.
  • No related research data.
  • No similar publications.