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Maiden, T.M.; Swanson, S.; Procopiou, P.A.; Harrity, J.P. (2016)
Publisher: American Chemical Society
Languages: English
Types: Article
The first Rh-catalyzed C-H amidation of pyridines is reported. The incorporation of a substituent at the C2 position both is crucial to the success of this transformation and provides considerable scope for further elaboration of the resulting products. Among these compounds, 2-chloropyridines allow access to a selection of intermediates including a versatile azaquinazoline scaffold.
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