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Drummond, Colin; Gilburt, Helen; Burns, Tom; Copello, Alex; Crawford, Michael; Day, Ed; Deluca, Paolo; Godfrey, Christine; Parrott, Steve; Rose, Abigail; Sinclair, Julia; Coulton, Simon (2016)
Publisher: Oxford University Press
Journal: Alcohol and Alcoholism (Oxford, Oxfordshire)
Languages: English
Types: Article
Subjects: HM, H, Original Manuscript
Aims: A pilot randomized controlled trial (RCT) to assess the feasibility and potential efficacy of\ud assertive community treatment (ACT) in adults with alcohol dependence.\ud Methods: Single blind, individually randomized, pilot RCT of 12 months of ACT plus treatment as\ud usual (TAU) versus TAU alone in adults (age 18+ years) with alcohol dependence and a history of previous\ud unsuccessful alcohol treatment attending specialist community alcohol treatment services.\ud ACT aimed to actively engage participants for 12 months with assertive, regular, minimum weekly\ud contact. ACT was combined with TAU. TAU comprised access to the full range of services provided\ud by the community teams. Primary outcome is mean drinks per drinking day and percent days abstinent\ud at 12 months follow up. Analysis of covariance was conducted using 80% confidence intervals,\ud appropriate in the context of a pilot trial.\ud Results: A total of 94 participants were randomized, 45 in ACT and 49 in TAU. Follow-up was\ud achieved with 98 and 88%, respectively at 12 months. Those in ACT had better treatment engagement,\ud and were more often seen in their homes or local community than TAU participants. At\ud 12 months the ACT group had more problems related to drinking and lower quality of life than TAU\ud but no differences in drinking measures. The ACT group had a higher percentage of days abstinent\ud but lower quality of life at 6 months. The ACT group had less unplanned healthcare use than TAU.\ud Conclusions: An trial of ACT was feasible to implement in an alcohol dependent treatment population.\ud Trial registration: ISRCTN22775534
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    • Burns T, Fiander M, Kent A, et al. (2000) Effects of case-load size on the process of care of patients with severe psychotic illness. Br J Psychiatry 177: 427-433.
    • Dieterich M, Irving CB, Park B, et al. (2010) Intensive case management for severe mental illness. Cochrane Database Syst Rev doi:10.1002/ 14651858.CD007906.pub2.
    • Department of Health. (2007) Drug Misuse and Dependence: UK Guidelines on Clinical Management. London: Department of Health (England), the Scottish Government, Welsh Assembly Government and Northern Ireland Executive.
    • Drummond C. (1990) The relationship between alcohol dependence and alcohol related problems in a clinical population. Br J Addict 85:357-366.
    • Drummond C, Coulton S, James D, et al. (2009) Effectiveness and cost effectiveness of stepped care intervention for alcohol use disorders in primary care: a pilot study. B J Psychiatry 195:448-456.
    • EuroQol Group. (1990) EuroQol: a new facility for the measurement of health-related quality of life. Health Policy 16:199-208.
    • Folstein MF, Folstein SE, McHugh PR. (1975) 'Mini-mental state': a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12:189-198.
    • Gilbert FS. (1998) The effect of type of aftercare follow-up on treatment outcome among alcoholics. J Stud Alcohol 49:149-159.
    • Gilburt H, Burns T, Copello A, et al. (2012) Assertive community treatment for alcohol dependence (ACTAD): study protocol for a randomised controlled trial. Trials 13:19.
    • Gilburt H, Sinclair J, Drummond C. (2015) Navigating the alcohol treatment pathway: a qualitative study from the service users' perspective. Alcohol Alcohol 50:444-450.
    • Heather N, Luce A, Peck D, et al. (1999) The development of a treatment version of the Readiness to Change Questionnaire. Addict Res 7:63-68.
    • Hilton ME, Maisto SA, Conigliaro J, et al. (2001) Improving alcoholism treatment across the spectrum of services. Alcohol Clin Exp Res 25: 128-135.
    • HM Government. (2012) The UK Government's Alcohol Strategy. London: HMSO.
    • Lim SS, Vos T, Flaxman AD, et al. (2012) A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 380:2224-2260.
    • Marshall EJ, Edwards JG, Taylor C. (1994) Mortality in men with drinking problems: a 20-year follow-up. Addiction 89:1293-1298.
    • McManus S, Meltzer H, Brugha T, et al. (2009) Adult Psychiatric Morbidity in England, 2007: Results of a Household Survey. Leeds: The NHS Information Centre for Health and Social Care.
    • Miller WR. (1995) Form 90: a structured assessment interview for drinking and related behaviours Project MATCH Monograph 5. Rockville, MD: National Institute on Alcohol Abuse and Alcoholism Mitchell AJ, Selmes T. (2007) A comparative survey of missed initial and follow-up appointments to psychiatric specialties in the United Kingdom. Psychiatr Serv 8:868-871.
    • National Institute for Health and Care Excellence. (2011) Alcohol Use Disorders: Diagnosis, Assessment and Management of Harmful Drinking and Alcohol Dependence. NICE Clinical Guideline 115. London: National Institute for Health and Clinical Excellence.
    • Passetti F, Jones G, Chawla K, et al. (2008) Pilot study of assertive community treatment methods to engage alcohol-dependent individuals. Alcohol Alcohol 43:451-455.
    • Robins LN, Wing J, Wittchen HU, et al. (1988) The Composite International Diagnostic Interview: an epidemiologic instrument suitable for use in conjunction with different diagnostic systems and in different cultures. Arch Gen Psychiatry 45:1069-1077.
    • Robinson KA, Dennison CR, Wayman DM, et al. (2007) Systematic review identifies number of strategies important for retaining study participants. J Clin Epidemiol 60:757-765.
    • Stockwell TR, Hodgson RJ, Edwards G, et al. (1979) The development of a questionnaire to measure severity of alcohol dependence. Br J Addict 74: 79-87.
    • Stout RL, Rubin A, Zwick W, et al. (1999) Optimizing the cost-effectiveness of alcohol treatment: a rationale for extended case monitoring. Addict Behav 24:17-35.
    • UKATT Research Team. (2005) Effectiveness of treatment for alcohol problems: findings of the randomised UK alcohol treatment trial (UKATT). Br Med J 331:541.
    • Ware JE Jr, Kosinski M, Keller SD. (1996) A 12 Item Short Form health survey: construction of scales and preliminary tests of reliability and validity. Med Care 34:220-233.
    • Woolard RH, Carty K, Wirtz P, et al. (2004) Follow-up of subjects in clinical trials: addressing subject attrition. Acad Emerg Med 11:859-866.
    • Zweben A, Fucito LM, O'Malley SS. (2009) Effective strategies for maintaining research participation in clinical trials. Drug Inf J 43, doi:10.1177/ 009286150904300411.
    • Zywiak WH, Longabaugh R, Wirtz PW. (2002) Decomposing the relationships between pre-treatment social network characteristics and alcohol treatment outcome. J Stud Alcohol 63:114-121.
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