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Huisman, M G; Veronese, G; Audisio, R A; Ugolini, G; Montroni, I; Vigano, A; Gilbert, L; Spiliotis, J; Stabilini, C; de Liguori Carino, N; Farinella, E; Stanojevic, G; Veering, B T; Reed, MW; Somasundar, P S; de Bock, G H; van Leeuwen, B L (2016)
Publisher: Elsevier
Languages: English
Types: Article
Subjects: R1
Background: Nutritional status (NS), though frequently affected in onco-geriatric patients, is no standard\ud part of a geriatric assessment. The aim of this study was to analyse the association between a preoperatively\ud impaired NS and geriatric domain impairments and adverse postoperative outcomes in onco-geriatric surgical patients.\ud Methods: 309 patients ≥70 years undergoing surgery for solid tumours were prospectively recruited. Nine screening tools were preoperatively administered as part of a geriatric assessment. NS was based on BMI, weight loss and food intake. Odds ratio’s (OR) and 95% confidence intervals (95%CI) were estimated using logistic regression analysis. The occurrence of 30-day adverse postoperative outcomes was recorded.\ud Results: At a median age of 76 years, 107 patients (34.6%) had an impaired NS. Decreased performance\ud status and depression were associated with an impaired NS, when adjusted for tumour characteristics and comorbidities (ORPS>1 3.46; 95%CI 1.56-7.67. ORGDS>5 2.11; 95%CI 1.05-4.26). An impaired NS was an independent predictor for major complications (OR 3.3; 95%CI 1.6-6.8). Ten out of 11 patients who deceased had an impaired NS.\ud Conclusion: An impaired NS is prevalent in onco-geriatric patients considered to be fit for surgery. It is associated with decreased performance status and depression. An impaired NS is a predictor for adverse postoperative outcomes. NS should be incorporated in a geriatric assessment.
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