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fbtwitterlinkedinvimeoflicker grey 14rssslideshare1
Languages: English
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Rationale\ud \ud Chronic obstructive pulmonary disease (COPD) is a progressive lung condition with extrapulmonary manifestations- cardiovascular diseases (CVD), impaired physical function, activity and increased frailty. Integrating measures of function into community assessments is hindered by the space and time required. The association of function, activity and CVD has not been extensively investigated in COPD.\ud \ud Objectives\ud \ud Explore the potential utility of Time Up and Go (TUG) as a measure of physical function in COPD\ud \ud Assess association of non-invasive measures of haemodynamics to physical function and self-reported activity\ud \ud Explore ambulatory haemodynamics in COPD and controls\ud \ud Methods\ud \ud Subjects with COPD (n=119) and controls (n=58) were recruited. Ethical and governance approvals were obtained. A medical history including falls, spirometry, peripheral and central haemodynamics, self-reported physical activity questionnaires and functional assessments (TUG and six-minute walk distance (6MWD)) were obtained from all subjects. Ambulatory 24-hour haemodynamics including aortic pulse wave velocity (aPWV) and blood pressure were measured in patients (n=20) and controls (n=19).\ud \ud Results\ud \ud TUG mean(SD) was increased in patients 11.9(3.7)s compared to controls 9.5(1.8)s, p<0.001. In patients, fallers had longer TUG than non-fallers (p=0.02) and a cut-off time of 12s had the highest sensitivity and specificity to detect fallers and non-fallers. Aortic stiffness was not associated to physical function or physical activity, p>0.05. In the pilot study, significant nocturnal dip in aPWV was seen in controls, p<0.01, but not in patients, p=0.07.\ud \ud Conclusion\ud \ud TUG could be a useful measure of function and possibly be incorporated into COPD assessment, particularly where time and space are limited. Finally, ambulatory haemodynamic machine, the Mobil-O-Graph, is feasible and offers opportunity to assess 24-hour haemodynamics profile including aPWV as opposed to a one-off measurement.
  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

    • α1AT
    • Table 1.1: Studies Investigating TUG in Patients with COPD .. Error! Bookmark not defined.
    • BHATT, S., COLE, A., WELLS, J., NATH, H., WATTS, J., COCKCROFT, J. & DRANSFIELD, M. 2014. Determinants of arterial stiffness in COPD. BMC Pulmonary Medicine, 14, 1.
    • BISCHOFF, H., STAHELIN, H., MONSCH, A., IVERSEN, M., WEYH, A., VON DECHEND, M., . . . THEILER, R. 2003. Identifying a cut-off point for normal mobility: a comparison of the timed 'up and go' test in community-dwelling and institutionalised elderly women. Age Ageing, 32, 315 - 320.
    • BLACHER, J., GUERIN, A. P., PANNIER, B., MARCHAIS, S. J., SAFAR, M. E. & LONDON, G. M. 1999. Impact of Aortic Stiffness on Survival in End-Stage Renal Disease. Circulation, 99, 2434-2439.
    • BLACHER, J. A. S., MICHEL 2005. Large-artery stiffness, hypertension and cardiovascular risk in older patients. Nat Clin Pract Cardiovasc Med, 2, 450- 455.
    • BOHADANA, A., TECULESCU, D. & MARTINET, Y. 2004. Mechanisms of chronic airway obstruction in smokers. Respiratory Medicine, 98, 139-151.
    • BOHANNON, R. 2006. Reference values for the timed up and go test: a descriptive meta-analysis. J Geriatr Phys Ther, 29, 64 - 68.
    • BOLTON, C., IONESCU, A., SHIELS, K., PETTIT, R., EDWARDS, P., STONE, M., . . . SHALE, D. 2004. Associated loss of fat-free mass and bone mineral density in chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 170, 1286 - 93.
    • BOLTON, C. E., BEVAN-SMITH, E. F., BLAKEY, J. D., CROWE, P., ELKIN, S. L., GARROD, R., . . . WALMSLEY, S. 2013. British Thoracic Society guideline on pulmonary rehabilitation in adults: accredited by NICE. Thorax, 68, ii1-ii30.
    • BOLTON, C. E., COCKCROFT, J. R., SABIT, R., MUNNERY, M., MCENIERY, C. M., WILKINSON, I. B., . . . BEN-SHLOMO, Y. 2009. Lung function in mid-life compared with later life is a stronger predictor of arterial stiffness in men: The Caerphilly Prospective Study. International Journal of Epidemiology, 38, 867-876.
    • BOLTON, C. E., MCENIERY, C. M., RAJ, V., MCDONNELL, B. J., DIXON, A. K., MUNNERY, M., . . . COCKCROFT, J. R. 2011. Aortic calcification, arterial stiffness and bone mineral density in patients with COPD. Artery Research, 5, 30-36.
    • BOOTH, S. & ADAMS, L. 2001. The shuttle walking test: a reproducible method for evaluating the impact of shortness of breath on functional capacity in patients with advanced cancer. Thorax, 56, 146-150.
    • BOREHAM, C. A., FERREIRA, I., TWISK, J. W., GALLAGHER, A. M., SAVAGE, M. J. & MURRAY, L. J. 2004. Cardiorespiratory Fitness, Physical Activity, and Arterial Stiffness: The Northern Ireland Young Hearts Project. Hypertension, 44, 721- 726.
    • BOUTOUYRIE, P., TROPEANO, A. I., ASMAR, R., GAUTIER, I., BENETOS, A., LACOLLEY, P. & LAURENT, S. 2002. Aortic Stiffness Is an Independent Predictor of Primary Coronary Events in Hypertensive Patients. Hypertension, 39, 10-15.
    • BROMBOSZCZ J, T. W. 2010. Tests of the functional performance of patients with COPD: A proposal for the application of the Expanded Timed 'Get Up and Go Test' (ETGUG). Medical Rehabilitation, 14, 22-34.
    • BRUNNER, E. J., SHIPLEY, M. J., WITTE, D. R., SINGH-MANOUX, A., BRITTON, A. R., TABAK, A. G., . . . KIVIMAKI, M. 2011. Arterial Stiffness, Physical Function, and Functional Limitation. Hypertension, 57, 1003-1009.
    • BURDON, J., JUNIPER, E., KILLIAN, K., HARGREAVE, F. & CAMPBELL, E. 1982. The perception of breathlessness in asthma. The American Review of Respiratory Disease, 126, 825-28.
    • BUTCHER, S. J., MESHKE, J. M. & SHEPPARD, M. S. 2004. Reductions in Functional Balance, Coordination, and Mobility Measures Among Patients With Stable Chronic Obstructive Pulmonary Disease. Journal of Cardiopulmonary Rehabilitation and Prevention, 24, 274-280.
    • BUTLAND RJ, P. J., GROSS ER, WOODCOCK AA, GEDDES DM 1982. Two-, six-, and 12- minute walking tests in respiratory disease. British Medical Journal Clinical Research Ed, 284, 1607-1608.
    • CAHALIN, L. P., MATHIER, M. A., SEMIGRAN, M. J., DEC, G. W. & DISALVO, T. G. 1996. The Six-Minute Walk Test Predicts Peak Oxygen Uptake and Survival in Patients With Advanced Heart Failure. Chest, 110, 325-332.
    • CAMILLI, A. E. R., D. ROYCE LEBOWITZ, MICHAEL D. 1991. Death Certificate Reporting of Confirmed Airways Obstructive Disease. American Journal of Epidemiology, 133, 795-800.
    • CAMP, P. G., O'DONNELL, D. E. & POSTMA, D. S. 2009. Chronic Obstructive Pulmonary Disease in Men and Women. Proceedings of the American Thoracic Society, 6, 535-538.
    • CASANOVA, C., CELLI, B. R., BARRIA, P., CASAS, A., COTE, C., DE TORRES, J. P., . . . AGUIRRE-JAIME, A. 2011. The 6-min walk distance in healthy subjects: reference standards from seven countries. European Respiratory Journal, 37, 150-156.
    • CASANOVA, C., COTE, C., MARIN, J. M., PINTO-PLATA, V., DE TORRES, J. P., AGUIRREJAÍME, A., . . . CELLI, B. R. 2008. Distance and Oxygen Desaturation During the 6-min Walk Test as Predictors of Long-term Mortality in Patients With COPD. Chest, 134, 746-752.
    • CASANOVA, C., COTE, C. G., MARIN, J. M., DE TORRES, J. P., AGUIRRE-JAIME, A., MENDEZ, R., . . . CELLI, B. R. 2007. The 6-min walking distance: long-term follow up in patients with COPD. European Respiratory Journal, 29, 535-540.
    • CASTAGNA, O., BOUSSUGES, A., NUSSBAUM, E., MARQUESTE, L. & BRISSWALTER, J. 2008. Peripheral arterial disease: an underestimated aetiology of exercise intolerance in chronic obstructive pulmonary disease patients. European Journal of Cardiovascular Prevention & Rehabilitation, 15, 270-277.
    • CDC 1997. Centers for Disease Control and Prevention. Mortality patterns: preliminary data, United States, 1996. MMWR Morbidity and Mortalily Weekly Report, 46, 941-944.
    • CELLI, B. R., COTE, C. G., MARIN, J. M., CASANOVA, C., MONTES DE OCA, M., MENDEZ, R. A., . . . CABRAL, H. J. 2004. The Body-Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity Index in Chronic Obstructive Pulmonary Disease. New England Journal of Medicine, 350, 1005-1012.
    • CELLI, B. R., MARIN, J. M., COTE, C. G., AGUIRRE, A. & MACARIO, C. C. 2009. Prognostic assessment of patients with COPD. The Lancet, 374, 1885.
    • CHANG, A., SEALE, H., WALSH, J. & BRAUER, S. 2008. Static balance is affected following an exercise task in chronic obstructive pulmonary disease. J Cardiopulm Rehabil Prev. , 28, 142-5.
    • CHANG ET AL, M., JISKA COHEN, LUIGI FERRUCI, SUZANNE LEVEILLE, STEFANO VOLPATO, NATHALIE DE REKENEIRE & JACK M. GURALNIK 2004. Incidence of Loss of Ability to Walk 400 Meters in a Functionally Limited Older Population. The American Geriatrics Society, 54, 737-742.
    • CHARLSON, M. E., POMPEI, P., ALES, K. L. & MACKENZIE, C. R. 1987. A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation. Journal of Chronic Diseases, 40, 373-383.
    • CHATILA, W. M., THOMASHOW, B. M., MINAI, O. A., CRINER, G. J. & MAKE, B. J. 2008. Comorbidities in Chronic Obstructive Pulmonary Disease. Proceedings of the American Thoracic Society, 5, 549-555.
    • CHEOL KIM, H., MOFARRAHI, M. & HUSSAIN, S. 2008. Skeletal muscle dysfunction in patients with chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis, 3, 637-658.
    • CLEMENT, D. L., DE BUYZERE, M. L., DE BACQUER, D. A., DE LEEUW, P. W., DUPREZ, D. A., FAGARD, R. H., . . . O'BRIEN, E. 2003. Prognostic Value of Ambulatory Blood-Pressure Recordings in Patients with Treated Hypertension. New England Journal of Medicine, 348, 2407-2415.
    • COTE, C. G., CASANOVA, C., MARÍN, J. M., LOPEZ, M. V., PINTO-PLATA, V., DE OCA, M. M., . . . CELLI, B. R. 2008. Validation and comparison of reference equations for the 6-min walk distance test. European Respiratory Journal, 31, 571-578.
    • COVITA. 2013. The Smokerlyzer® Breath CO Test Instructions and Tips [Online]. USA: coVita. Available: http://www.covita.net/pdfs/Smokerlyzer%20Test%20and%20Tips%20- %20COmpact.pdf [Accessed 27/9 2012].
    • CRUICKSHANK, K., RISTE, L., ANDERSON, S. G., WRIGHT, J. S., DUNN, G. & GOSLING, R. G. 2002. Aortic Pulse-Wave Velocity and Its Relationship to Mortality in Diabetes and Glucose Intolerance. Circulation, 106, 2085-2090.
    • CURB, J. D., CERIA-ULEP, C. D., RODRIGUEZ, B. L., GROVE, J., GURALNIK, J., WILLCOX, B. J., . . . CHEN, R. 2006. Performance-Based Measures of Physical Function for High-Function Populations. Journal of the American Geriatrics Society, 54, 737-742.
    • CURKENDALL, S. M., DELUISE, C., JONES, J. K., LANES, S., STANG, M. R., GOEHRING JR, E. & SHE, D. 2006. Cardiovascular Disease in Patients with Chronic Obstructive Pulmonary Disease, Saskatchewan Canada: Cardiovascular Disease in COPD Patients. Annals of Epidemiology, 16, 63-70.
    • CWIKEL, J., FRIED, V., BIDERMAN, A. & GALINSKY, D. 1998. Validation of a fall-risk screening test, the Elderly Fall Screening Test (EFST), for community-dwelling elderly. Disability and Rehabilitation, 20, 161-167.
    • DE LUCA, N., ASMAR, R., LONDON, G., O'ROURKE, M. & SAFAR, M. 2004. Selective reduction of cardiac mass and central blood pressure on low-dose combination perindopril/indapamide in hypertensive subjects. J Hypertens, 22, 1623 - 1630.
    • DE TORRES, J. P., PINTO-PLATA, V., INGENITO, E., BAGLEY, P., GRAY, A., BERGER, R. & CELLI, B. 2002. Power of Outcome Measurements to Detect Clinically Significant Changes in Pulmonary Rehabilitation of Patients With COPD. Chest, 121, 1092-1098.
    • DECRAMER, M., VESTBO, J., BOURBEAU, J., CELLI, B., HUI, D. & VARELA, E. 2014. Global initiative for Chronic Obstructive Lung Disease: Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. .
    • DEGENS, R. C. W. A. H. 2007. Factors contributing to muscle wasting and dysfunction in COPD patients. International Journal of COPD, 2, 289-300.
    • DELISA FAIRWEATHER, S. F.-K., AND NOEL R. ROSE 2008. Sex Differences in Autoimmune Disease from a Pathological Perspective. Am J Pathol, 3, 600- 609.
    • DEMEDTS, K., MOREL-MONTERO, A., LEBECQUE, S., PACHECO, Y., CATALDO, D., JOOS, F., . . . BRUSSELLE, G. 2006. Elevated MMP-12 protein levels in induced sputum from patients with COPD. Thorax, 61, 196-201.
    • DEPEW, Z. S., KARPMAN, C., NOVOTNY, P. J. & BENZO, R. P. 2013. Correlations Between Gait Speed, 6-Minute Walk Distance, Physical Activity, and SelfEfficacy in Patients With Severe Chronic Lung Disease. Respiratory Care, 58, 2113-2119.
    • EARHART, M. J. F. A. G. M. 2009. Reference Equation for the Six-Minute Walk in Individuals with Parkinson Disease. J Rehabil Res Dev, 46, 1121-1126.
    • EISNER, M., BLANC, P., SIDNEY, S., YELIN, E., LATHON, P., KATZ, P., . . . IRIBARREN, C. 2007. Body composition and functional limitation in COPD. Respiratory Research, 8, 7.
    • EISNER, M. D., BLANC, P. D., YELIN, E. H., SIDNEY, S., KATZ, P. P., ACKERSON, L., . . . IRIBARREN, C. 2008. COPD as a Systemic Disease: Impact on Physical Functional Limitations. The American Journal of Medicine, 121, 789-796.
    • ELLIOT, L. & IQBAL, P. 2003. Factors associated with probability of patient rejecting a repeat 24 h ambulatory blood pressure monitoring, despite recommendation by the physician. Blood pressure monitoring, 8, 191-194.
    • ENGSTRÖM, G., WOLLMER, P., HEDBLAD, B., JUUL-MÖLLER, S., VALIND, S. & JANZON, L. 2001. Occurrence and Prognostic Significance of Ventricular Arrhythmia Is Related to Pulmonary Function : A Study From "Men Born in 1914," Malmö, Sweden. Circulation, 103, 3086-3091.
    • ENRIGHT, P. L., MCBURNIE, M. A., BITTNER, V., TRACY, R. P., MCNAMARA, R., ARNOLD, A. & NEWMAN, A. B. 2003. The 6-min Walk Test. Chest, 123, 387- 398.
    • EWING, G., GREANEY, M., RIEBE, D., NIGG, C., BURBANK, P. & CLARK, P. 2010. Physical and mental health-related correlates of physical function in community dwelling older adults: a cross sectional study. BMC Geriatrics, 10.
    • EZZELL, L. & JENSEN, G. L. 2000. Malnutrition in chronic obstructive pulmonary disease. The American Journal of Clinical Nutrition, 72, 1415-1416.
    • FLANSBJER, U. B., HOLMBACK, A. M., DOWNHAM, D., PATTEN, C. & LEXELL, J. 2005. Reliability of gait performance tests in men and women with hemiparesis after stroke. Journal of rehabilitation medicine : official journal of the UEMS European Board of Physical and Rehabilitation Medicine, 37, 75-82.
    • FLETCHER, C. 1960. Standardised questionnaire on respiratory symtoms: a statement prepared and approved by the MRC Committee on the Aetiology of Chronic Bronchitis (MRC breathlessness score). BMJ, 2, 1665.
    • FOWLER, S. J., SINGH, S. J. & REVILL, S. 2005. Reproducibility and validity of the incremental shuttle walking test in patients following coronary artery bypass surgery. Physiotherapy, 91, 22-27.
    • FRANKLIN, S., GUSTIN, W., WONG, N., LARSON, M., WEBER, M. & KANNEL, W. 1997. Hemodynamic patterns of age-related changes in blood pressure. The Framingham Heart Study. Circulation, 96, 308 - 315.
    • FREEDMAN, V. A. & MARTIN, L. G. 1998. Understanding trends in functional limitations among older Americans. American Journal of Public Health, 88, 1457-1462.
    • FREEMAN, E. E., BROMAN, A. T., TURANO, K. A. & WEST, S. K. 2008. MotionDetection Threshold and Measures of Balance in Older Adults: The SEE Project. Investigative Ophthalmology & Visual Science, 49, 5257-5263.
    • FRETER, S. H. & FRUCHTER, N. 2000. Relationship between timed 'up and go' and gait time in an elderly orthopaedic rehabilitation population. Clinical Rehabilitation, 14, 96-101.
    • GALE, N., DUCKERS, J., ENRIGHT, S., COCKCROFT, J., SHALE, D. & BOLTON, C. 2011. Does pulmonary rehabilitation address cardiovascular risk factors in patients with COPD? BMC Pulmonary Medicine, 11, 20.
    • GALIÈ, N., TORBICKI, A., BARST, R., DARTEVELLE, P., HAWORTH, S., HIGENBOTTAM, T., . . . SIMONNEAU, G. 2004. Guidelines on diagnosis and treatment of pulmonary arterial hypertension. European Heart Journal, 25, 2243-2278.
    • GARCIA-AYMERICH, J., SERRA, I., GÓMEZ, F. P., FARRERO, E., BALCELLS, E., RODRÍGUEZ, D. A., . . . GROUP, C. O. C. S. 2009. Physical Activity and Clinical and Functional Status in COPD. Chest, 136, 62-70.
    • GARCIA-RIO, F., ROJO, B., CASITAS, R., LORES, V., MADERO, R., ROMERO, D., . . . VILLASANTE, C. 2012. Prognostic value of the objective measurement of daily physical activity in patients with copd. Chest, 142, 338-346.
    • GEIJER, R. M. M., SACHS, A. P. E., VERHEIJ, T. J. M., KERSTJENS, H. A. M., KUYVENHOVEN, M. M. & HOES, A. W. 2007. Quality of life in smokers: focus on functional limitations rather than on lung function? British Journal of General Practice, 57, 477-482.
    • GILES, T. D., OPARIL, S., OFILI, E. O., PITT, B., PURKAYASTHA, D., HILKERT, R., . . . SOWERS, J. R. 2011. The role of ambulatory blood pressure monitoring compared with clinic and home blood pressure measures in evaluating moderate versus intensive treatment of hypertension with amlodipine/valsartan for patients uncontrolled on angiotensin receptor blocker monotherapy. Blood Press Monit, 16, 87-95.
    • GIMENO-SANTOS, E., FREI, A., STEURER-STEY, C., DE BATLLE, J., RABINOVICH, R. A., RASTE, Y., . . . CONSORTIUM, O. B. O. P. 2014. Determinants and outcomes of physical activity in patients with COPD: a systematic review. Thorax.
    • GLOBAL INITIATIVE FOR CHRONIC OBSTRUCTIVE LUNG DISEASE GOLD. 2011. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease [Online]. Available: http://www.goldcopd.org/uploads/users/files/GOLD_Report_2014_Jun11.pd f 2014].
    • GODTFREDSEN, N. S., VESTBO, J., OSLER, M. & PRESCOTT, E. 2002. Risk of hospital admission for COPD following smoking cessation and reduction: a Danish population study. Thorax, 57, 967-972.
    • GOLD, D. R., WANG, X., WYPIJ, D., SPEIZER, F. E., WARE, J. H. & DOCKERY, D. W. 1996. Effects of Cigarette Smoking on Lung Function in Adolescent Boys and Girls. New England Journal of Medicine, 335, 931-937.
    • GRIFFITHS, T. L., BURR, M. L., CAMPBELL, I. A., LEWIS-JENKINS, V., MULLINS, J., SHIELS, K., . . . TUNBRIDGE, J. 2000. Results at 1 year of outpatient multidisciplinary pulmonary rehabilitation: a randomised controlled trial. The Lancet, 355, 362-368.
    • GURALNIK, J. M., SIMONSICK, E. M., FERRUCCI, L., GLYNN, R. J., BERKMAN, L. F., BLAZER, D. G., . . . WALLACE, R. B. 1994. A Short Physical Performance Battery Assessing Lower Extremity Function: Association With Self-Reported Disability and Prediction of Mortality and Nursing Home Admission. Journal of Gerontology, 49, M85-M94.
    • GYRD THRANE, R. M. J. A. E. T. 2007. The association between timed up and go test and history of falls: The Tromsø study. BMC Geriatrics, 7, 1-7.
    • HALL, I. P. & LOMAS, D. A. 2010. The genetics of obstructive lung disease: big is beautiful. Thorax, 65, 760-761.
    • HARADA, N. D., CHIU, V. & STEWART, A. L. 1999. Mobility-related function in older adults: Assessment with a 6-minute walk test. Archives of physical medicine and rehabilitation, 80, 837-841.
    • HART, C., DAVEY SMITH, G., GRUER, L. & WATT, G. 2010. The combined effect of smoking tobacco and drinking alcohol on cause-specific mortality: a 30 year cohort study. BMC Public Health, 10, 789.
    • HAWKINS, M., GABRIEL, K. P., COOPER, J., STORTI, K. L., SUTTON-TYRRELL, K. & KRISKA, A. 2014. The impact of change in physical activity on change in arterial stiffness in overweight or obese sedentary young adults. Vascular Medicine, 19, 257-263.
    • HERMAN, T., GILADI, N. & HAUSDORFFA, J. 2011. Properties of the 'Timed Up and Go' Test: More than Meets the Eye. Gerontology, 57, 203-210.
    • HERNANDES, N. A., WOUTERS, E. F. M., MEIJER, K., ANNEGARN, J., PITTA, F. & SPRUIT, M. A. 2011. Reproducibility of 6-minute walking test in patients with COPD. European Respiratory Journal, 38, 261-267.
    • HERSH, C. P., DAHL, M., LY, N. P., BERKEY, C. S., NORDESTGAARD, B. G. & SILVERMAN, E. K. 2004. Chronic obstructive pulmonary disease in α1-antitrypsin PI MZ heterozygotes: a meta-analysis. Thorax, 59, 843-849.
    • HEUNG, T. & SHAMAY, S. 2009. Effect of seat height and turning direction on the Timed Up and Go test scores of people after stroke. J Rehabil Med, 41, 719- 722.
    • HICKSON, S. S., BUTLIN, M., BROAD, J., AVOLIO, A. P., WILKINSON, I. B. & MCENIERY, C. M. 2009. Validity and repeatability of the Vicorder apparatus: a comparison with the SphygmoCor device. Hypertens Res, 32, 1079-1085.
    • HIRANO, K., IMAGAMA, S., HASEGAWA, Y., ITO, Z., MURAMOTO, A. & ISHIGURO, N. 2013. Impact of low back pain, knee pain, and timed up-and-go test on quality of life in community-living people. Journal of Orthopaedic Science, 1- 8.
    • HNIZDO, E., SULLIVAN, P. A., BANG, K. M. & WAGNER, G. 2002. Association between Chronic Obstructive Pulmonary Disease and Employment by Industry and Occupation in the US Population: A Study of Data from the Third National Health and Nutrition Examination Survey. American Journal of Epidemiology, 156, 738-746.
    • HODGKINSON J, M. J., MARTIN U, GUO B, HOBBS FD, DEEKS JJ, HENEGHAN C, ROBERTS N, MCMANUS RJ. 2011. Relative effectiveness of clinic and home blood pressure monitoring compared with ambulatory blood pressure monitoring in diagnosis of hypertension: systematic review. BMJ, 342.
    • HOLLAND, A. E., HILL, C. J., RASEKABA, T., LEE, A., NAUGHTON, M. T. & MCDONALD, C. F. 2010. Updating the Minimal Important Difference for Six-Minute Walk Distance in Patients With Chronic Obstructive Pulmonary Disease. Archives of physical medicine and rehabilitation, 91, 221-225.
    • HUIART, L., ERNST, P. & SUISSA, S. 2005. Cardiovascular Morbidity and Mortality in COPD. Chest, 128, 2640-2646.
    • HUNNINGHAKE, D. B. 2005. Cardiovascular Disease in Chronic Obstructive Pulmonary Disease. Proceedings of the American Thoracic Society, 2, 44-49.
    • JANSSEN, D., FRANSSEN, F., WOUTERS, E., SCHOLS, J. & SPRUIT, M. 2011. Impaired health status and care dependency in patients with advanced COPD or chronic heart failure. Quality of Life Research, 20, 1679-1688.
    • JANSSEN, I. & ROSS, R. 2012. Vigorous intensity physical activity is related to the metabolic syndrome independent of the physical activity dose. International Journal of Epidemiology, 41, 1132-1140.
    • JANSSENS, J. P., PACHE, J. C. & NICOD, L. P. 1999. Physiological changes in respiratory function associated with ageing. European Respiratory Journal, 13, 197-205.
    • JOHN, M., HUSSAIN, S., PRAYLE, A., SIMMS, R., COCKCROFT, J. R. & BOLTON, C. E. 2013. Target renal damage: the microvascular associations of increased aortic stiffness in patients with COPD. Respir Res, 14, 31.
    • JONES, C. R., TAYLOR, K., CHOWIENCZYK, P., POSTON, L. & SHENNAN, A. H. 2000. A validation of the Mobil O Graph (version 12) ambulatory blood pressure monitor. Blood pressure monitoring, 5, 233-238.
    • JONES, P., QUIRK, F., BAVEYSTOCK, C. & LITTLEJOHNS, P. 1992. A self-complete measure of health status for chronic airflow limitation. The St. George's Respiratory Questionnaire. AM REV RESPIR DIS, 145, 1321 - 1327.
    • KAESS, B. M., RONG, J., LARSON, M. G. & ET AL. 2012. AOrtic stiffness, blood pressure progression, and incident hypertension. JAMA, 308, 875-881.
    • KALLEM, R. R., MEYERS, K. E. C., SAWINSKI, D. L. & TOWNSEND, R. R. 2013. A Comparison of Two Ambulatory Blood Pressure Monitors Worn at the Same Time. The Journal of Clinical Hypertension, 15, 321-325.
    • KARIO, K., PICKERING, T. G., MATSUO, T., HOSHIDE, S., SCHWARTZ, J. E. & SHIMADA, K. 2001a. Stroke Prognosis and Abnormal Nocturnal Blood Pressure Falls in Older Hypertensives. Hypertension, 38, 852-857.
    • KARIO, K., SHIMADA, K., SCHWARTZ, J. E., MATSUO, T., HOSHIDE, S. & PICKERING, T. G. 2001b. Silent and clinically overt stroke in older Japanese subjects with white-coat and sustained hypertension. Journal of the American College of Cardiology, 38, 238-245.
    • KATAJISTO M, K. H., RANTANEN P, LINDQVIST A, KILPELÄINEN M, TIKKANEN H, LAITINEN T 2012. Physical inactivity in COPD and increased patient perception of dyspnea. International Journal of Chronic Obstructive Pulmonary Disease, 7, 743-755
    • KELLY, R., HAYWARD, C., AVOLIO, A. & O'ROURKE, M. 1989. Noninvasive determination of age-related changes in the human arterial pulse. Circulation, 80, 1652-1659.
    • KESANIEMI YK, D. E., JENSEN, KOPELMAN, LEFÈBVRE, REEDER. 2001. Dose-response issues concerning physical activity and health: an evidence-based symposium. Med Sci Sports Exerc, 33, S351-8.
    • KHANDELWAL, M., MAHESHWARI, V., GARG, S., KUMAR, K., GUPTA, R. & KHANDELWAL, S. 2013. Six minute walk distance: Correlation with spirometric & clinical parameters in chronic obstructive pulmonary disease. International J. of Healthcare & Biomedical Research, 1, 217-226.
    • KIERS, H. D., HOFSTRA, J. M. & WETZELS, J. F. M. 2008. Oscillometric blood pressure measurements: Differences between measured and calculated mean arterial pressure. Netherlands Journal of Medicine, 66, 474-479.
    • KON, S. S. C., CANAVAN, J. L., NOLAN, C. M., CLARK, A. L., JONES, S. E., CULLINAN, P., . . . MAN, W. D.-C. 2014. What the 4-metre gait speed measures and why it cannot replace functional capacity tests. European Respiratory Journal, 43, 1820-1822.
    • KON, S. S. C., PATEL, M. S., CANAVAN, J. L., CLARK, A. L., JONES, S. E., NOLAN, C. M., . . . MAN, W. D.-C. 2013. Reliability and validity of 4-metre gait speed in COPD. European Respiratory Journal, 42, 333-340.
    • MACKENZIE, S., MCENIERY, M., DHAKAM, Z., BROWN, J., COCKCROFT, R. & WILKINSON, B. 2009. Comparison of the Effects of Antihypertensive Agents on Central Blood Pressure and Arterial Stiffness in Isolated Systolic Hypertension. Hypertension, 54, 409-413.
    • MACLAY, J. D., MCALLISTER, D. A., MILLS, N. L., PATERSON, F. P., LUDLAM, C. A., DROST, E. M., . . . MACNEE, W. 2009. Vascular Dysfunction in Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine, 180, 513-520.
    • MADUREIRA, M. M., TAKAYAMA, L., GALLINARO, A. L., CAPARBO, V. F., COSTA, R. A. & PEREIRA, R. M. R. 2007. Balance training program is highly effective in improving functional status and reducing the risk of falls in elderly women with osteoporosis: a randomized controlled trial. Osteoporosis International, 18, 419-425.
    • MANCIA, G., FAGARD, R., NARKIEWICZ, K., REDON, J., ZANCHETTI, A., BÖHM, M., . . . WOOD, D. A. 2013. 2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). European Heart Journal, 34, 2159-2219.
    • MANGIONE, K. K., CRAIK, R. L., MCCORMICK, A. A., BLEVINS, H. L., WHITE, M. B., SULLIVAN-MARX, E. M. & TOMLINSON, J. D. 2010. Detectable Changes in Physical Performance Measures in Elderly African Americans. Physical Therapy, 90, 921-927.
    • MANNINO, D., D., H., AKINBAMI, L., FORD, E. & REDD, S. 2002. Chronic Obstructive Pulmonary Disease Surveillance --- United States, 1971--2000. Centers for Disease Control and Prevention - Morbidity and Mortality Weekly Report, 51, 1-16.
    • MANNINO, D. M., THORN, D., SWENSEN, A. & HOLGUIN, F. 2008. Prevalence and outcomes of diabetes, hypertension and cardiovascular disease in COPD. European Respiratory Journal, 32, 962-969.
    • MANNINO ET AL, R. C. G., MS; THOMAS L. PETTY, MD; EVA LYDICK, PHD 2000. Obstructive Lung Disease and Low Lung Function in Adults in the United States. Arch Intern Med, 160, 1683-1689.
    • MARIA-CHRISTINA L. MACHADO, J. A. K., SONIA A. BUIST, ANDREW L. BILDERBACK, GUILHERME P. FAZOLO, MICHELLE G. SANTAROSA, FERNANDO QUEIROGA, JR., AND WILLIAM M. VOLLMER 2006. Sex Differences in Survival of Oxygendependent Patients with Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med, 174, 524-529.
    • MARK WEWERS, M. 1989. Pathogenesis of Emphysema Assessment of Basic Science Concepts Through Clinical Investigation. Chest, 95, 190-95.
    • MATHIAS, S., NAYAK, U. S. & ISAACS, B. 1986. Balance in elderly patients: the "get-up and go" test. Archives of physical medicine and rehabilitation, 67, 387-9.
    • MATTACE-RASO, F., VAN DER CAMMEN, T., HOFMAN, A., VAN POPELE, N., BOS, M., SCHALEKAMP, M., . . . BRETELER, M. 2006. Arterial stiffness and risk of coronary heart disease and stroke: the rotterdam study. Circulation, 113, 657 - 663.
    • MCALLISTER, D., MACLAY, J., MILLS, N., MAIR, G., MILLER, J., ANDERSON, D., . . . MACNEE, W. 2007. Arterial stiffness is independently associated with emphysema severity in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 176, 1208 - 14.
    • MCENIERY, C. M., YASMIN, HALL, I. R., QASEM, A., WILKINSON, I. B., COCKCROFT, J. R. & ON BEHALF OF THE ACCT INVESTIGATORS 2005. Normal Vascular Aging: PERERA, S., SAMIR, H., RICHARD, C. & STEPHANIE, S. 2006. Meaningful Change and Responsiveness in Common Physical Performance Measures in Older Adults. The American Geriatrics Society, 54, 743-749.
    • PERUZZA S, S. G., VIANELLO A, PISENT C, TIOZZO F, MANZAN A, COIN A, INELMEN EM, ENZI G. 2003. Chronic obstructive pulmonary disease (COPD) in elderly subjects: impact on functional status and quality of life. RESPIRATORY MEDICINE, 97, 612-617.
    • PICKERING, T. G., DAVIDSON, K., GERIN, W. & SCHWARTZ, J. E. 2002. Masked Hypertension. Hypertension, 40, 795-796.
    • PICKERING, T. G., HALL, J. E., APPEL, L. J., FALKNER, B. E., GRAVES, J., HILL, M. N., . . . ROCCELLA, E. J. 2005. Recommendations for Blood Pressure Measurement in Humans and Experimental Animals: Part 1: Blood Pressure Measurement in Humans: A Statement for Professionals From the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research. Circulation, 111, 697-716.
    • PINTO-PLATA, V. M., COTE, C., CABRAL, H., TAYLOR, J. & CELLI, B. R. 2004. The 6‐min walk distance: change over time and value as a predictor of survival in severe COPD. European Respiratory Journal, 23, 28-33.
    • PITTA, F., TROOSTERS, T., SPRUIT, M., PROBST, V., DECRAMER, M. & GOSSELINK, R. 2005a. Characteristics of physical activities in daily life in chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 171, 972 - 977.
    • PITTA, F., TROOSTERS, T., SPRUIT, M. A., PROBST, V. S., DECRAMER, M. & GOSSELINK, R. 2005b. Characteristics of Physical Activities in Daily Life in Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine, 171, 972-977.
    • PODSIADLO, D. & RICHARDSON, S. 1991. The timed "Up & Go": a test of basic functional mobility for frail elderly persons. J Am Geriatr Soc, 39, 142 - 148.
    • POULAIN, M., DURAND, F., PALOMBA, B., CEUGNIET, F., DESPLAN, J., VARRAY, A. & PRÉFAUT, C. 2003. 6-Minute Walk Testing Is More Sensitive Than Maximal Incremental Cycle Testing for Detecting Oxygen Desaturation in Patients With COPD*. Chest, 123, 1401-1407.
    • PRAKASH, R. 2014. Physical inactivity a leading cause of disease and disability, warns WHO
    • Available: http://www.who.int/mediacentre/news/releases/release23/en/.
    • PRESCOTT, E., LANGE, P. & VESTBO, J. 1999. Socioeconomic status, lung function and admission to hospital for COPD: results from the Copenhagen City Heart Study. European Respiratory Journal, 13, 1109-1114.
    • PRINCE, S., ADAMO, K., HAMEL, M., HARDT, J., GORBER, S. & TREMBLAY, M. 2008. A comparison of direct versus self-report measures for assessing physical activity in adults: a systematic review. International Journal of Behavioral Nutrition and Physical Activity, 5, 56.
    • PUHAN, M. A., GARCIA-AYMERICH, J., FREY, M., TER RIET, G., ANTÓ, J. M., AGUSTÍ, A. G., . . . HELD, U. 2009. Expansion of the prognostic assessment of patients with chronic obstructive pulmonary disease: the updated BODE index and the ADO index. The Lancet, 374, 704-711.
    • PUHAN, M. A., HANSEL, N. N., SOBRADILLO, P., ENRIGHT, P., LANGE, P., HICKSON, D., . . . GARCIA-AYMERICH, J. 2012. Large-scale international validation of the ADO index in subjects with COPD: an individual subject data analysis of 10 cohorts. BMJ Open, 2.
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