LOGIN TO YOUR ACCOUNT

Username
Password
Remember Me
Or use your Academic/Social account:

CREATE AN ACCOUNT

Or use your Academic/Social account:

Congratulations!

You have just completed your registration at OpenAire.

Before you can login to the site, you will need to activate your account. An e-mail will be sent to you with the proper instructions.

Important!

Please note that this site is currently undergoing Beta testing.
Any new content you create is not guaranteed to be present to the final version of the site upon release.

Thank you for your patience,
OpenAire Dev Team.

Close This Message

CREATE AN ACCOUNT

Name:
Username:
Password:
Verify Password:
E-mail:
Verify E-mail:
*All Fields Are Required.
Please Verify You Are Human:
fbtwitterlinkedinvimeoflicker grey 14rssslideshare1
Publisher: IOP Publishing
Languages: English
Types: Article
Subjects: G900, C800
This work focuses on methods for investigation of physiological time series based on complexity analysis. It is a part of a wider programme to determine non-invasive markers for healthy ageing. We consider two case studies investigated with actigraphy: (a) sleep and alternations with insomnia, and (b) ageing effects on mobility patterns. We illustrate, using these case studies, the application of fractal analysis to the investigation of regulation patterns and control, and change of physiological function. In the first case study, fractal analysis techniques were implemented to study the correlations present in sleep actigraphy for individuals suffering from acute insomnia in comparison with healthy controls. The aim was to investigate if complexity analysis can detect the onset of adverse health-related events. The subjects with acute insomnia displayed significantly higher levels of complexity, possibly a result of too much activity in the underlying regulatory systems. The second case study considered mobility patterns during night time and their variations with age. It showed that complexity metrics can identify change in physiological function with ageing. Both studies demonstrated that complexity analysis can be used to investigate markers of health, disease and healthy ageing.
  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

    • [1] Mandelbrot BB 1983 The Fractal Geometry of Nature (New York: Freeman) 1-58
    • [2] Lewis A, Lipsitz LA and Goldberger AL 1992 JAMA 267(13) 1806-1809
    • [3] Dauwels J, Vialatte F and Cichocki A 2010 Current Alzheimer Research 7(6) 487-505
    • [4] Holloway P, Angelova M, Lombardo S, St Clair Gibson A and Lee D Ellis J 2014 J R Soc Interface 20131112
    • [5] Holloway P, Angelova M, St Clair Gibson A, Lombardo S, Lee D, Ellis J, Lambert and Rauch L 2012 Modelling techniques for analysis of human activity patterns. Intelligent Systems IS12, Proceedings of the 6th IEEE International Conference, 6-8 September 2012 Sofia, 275-280
    • [6] Lichstein KL, Stone KC, Donaldson J, Nau SD, Soeffing JP, Murray D, Lester KW and Aguillard RN 2006 SLEEP 29 (2) 232-239
    • [7] Lipsitz LA 2002 J. Gerontol. Biol. Sci. 57A (3) B115-B125
    • [8] Melo RC, Santos MDB, Silva E, Quitrio RJ, Moreno MA, Reis MS, Verzola IA, Oliveira L, Martins LEB, Gallo-Junior L and Catai AM 2005 Braz. J. Med. Biol. Res. 38 1331-1338
    • [9] Blackledge JM 2005 Digital Image Processing: Mathematical and computational methods (West Sussex: Horwood Publishing)
    • [10] Akselrod S, Gordon D, Ubel FA, Shannon DC, Barger AC and Cohen RJ 1981 Science, New Science 213 (4504) 220-222
    • [11] Ivanov PCh, Amaral LAN, Goldberger AL, Havlin S, Rosenblum MG, Struzik ZR and Stanley HE 1999 Nature 399 461-465
    • [12] Valencia JF 2009 IEEE Eng. Med. Biol. Mag. 28 72-78
    • [13] Goldberger AL Amaral LA, Hausdorff JM, Ivanov P, Peng CK and Stanley HE 2002 PNAS USA 99 2466- 2472
    • [14] Goldberger AL, Moody GB and Costa MD 2012 available online at http://physionet.org/tutorials/cv/
    • [15] Peng CK, Buldyrev SV, Havlin S, Simons M, Stanley HE and Goldberger AL 1994 Phys. Rev. E. 49 1685- 1689
    • [16] Tulppo MP, Hautala AJ, Makikallio TH, Laukkanen RT, Nissila S, Hughson RL and Huikuri HV 2003 J. Appl. Physiol. 95 364-372
    • [17] Yazawa T, Asai I, Shimoda Y and Katsuyama T 2010 WCECS 2 921-925
    • [18] Kantelhardt JW, Ashkenazy Y, Ivanov PCh, Bunde A, Havlin S, Penzel T, Peter J-H and Stanley HE 2002 Phys. Rev. E 65 (5) 051908
    • [19] Mietus JE, Peng CK, Ivanov PCh and Goldberger AL 2000 Comput. Cardiol. 27 753-756
    • [20] Penzel T, Kantelhardt JW, Becker HF, Peter JH and Bunde A 2003 Comput. Cardiol. 30 307-310
    • [21] Ivanov PCh, Bunde A, Amaral LAN, Havlin S, Fritsch-Yelle J, Baevsky RM, Stanley HE and Goldberger AL 1999 Europhys. Lett. 48 (5) 594-600
    • [22] Ashkenazy Y, Ivanov PCh, Havlin S, Peng C-K, Goldberger AL and Stanley HE 2001 Phys. Rev. Lett. 86 (9) 1900-1903
    • [23] Ashkenazy Y, Ivanov PCh, Havlin S, Peng CK, Yamamoto Y, Goldberger AL and Stanley HE 2000 Comput. Cardiol. 27 139-142
    • [24] Ashkenazy Y, Havlin S, Ivanov PCh, Peng CK, Schulte-Frohlinde V and Stanley HE 2003 Physica A 323 19-41
    • [25] Buysse DJ., Cheng Y, Germain A., Moul DE, Franzen P, Fletcher M and Monk TH 2010 Sleep Med. 11 56-71
    • [26] Peng CK and Havlin S, Stanley HE and Goldberger AL 1995 Chaos 5 82-87
    • [27] Wohlfahrt P, Kantelhardt JW, Zinkhan M, Schumann AY, Penzel T, Fietze I, Pillmann F and Stang A 2013 EPL 103 68002
    • [28] Hu K, Ivanov PCh, Chen Z, Hilton MF, Stanley HE and Shea SA 2004 Physica A 337 307-318
    • [29] Schneider-Helmert D 1987 Sleep 10 (5) 452-462
    • [30] Jurysta F, Lanquart JP, Sputaels V, Dumont M, Migeotte PF, Leistedt S, Linkowski P and van de Borne P 2009 Clin. Neurophysiol. 120 (6) 1054-1060
    • [31] Sadeh A, Hauri PJ, Kripke DF and Lavie P 1995 Sleep 18 288-302
    • [32] Ivanov PCh, Hu K, Hilton MF, Shea SA and Stanley HE 2007 PNAS 104 (52) 20702-20707
    • [33] Chen Z, Ivanov PCh, Hu K and Stanley HE 2002 Phys. Rev. E 65 (4)
  • No related research data.
  • No similar publications.

Share - Bookmark

Funded by projects

  • EC | MATSIQEL

Cite this article