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Johnson, Tarn C.; Totty, William; Wills, Martin (2012)
Publisher: American Chemical Society
Languages: English
Types: Article
Subjects: QD
The synthesis of a series of tridentate ligands based on a homochiral 1,2-diamine structure attached to a triazole group and their subsequent applications to the asymmetric transfer hydrogenation of ketones are described. In the best cases, alcohols of up to 93% ee were obtained. Although base is not required, the use of Ru3(CO)12 as metal source is essential, indicating a unique mechanism for the formation of the active catalyst.
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