Remember Me
Or use your Academic/Social account:


Or use your Academic/Social account:


You have just completed your registration at OpenAire.

Before you can login to the site, you will need to activate your account. An e-mail will be sent to you with the proper instructions.


Please note that this site is currently undergoing Beta testing.
Any new content you create is not guaranteed to be present to the final version of the site upon release.

Thank you for your patience,
OpenAire Dev Team.

Close This Message


Verify Password:
Verify E-mail:
*All Fields Are Required.
Please Verify You Are Human:
fbtwitterlinkedinvimeoflicker grey 14rssslideshare1
Kurien, Thomas; Kerslake, Robert; Haywood, Brett; Pearson, Richard G.; Scammell, Brigitte E. (2016)
Publisher: Hindawi Publishing Corporation
Journal: Case Reports in Orthopedics
Languages: English
Types: Report
Subjects: Orthopedic surgery, RD701-811, Case Report, Article Subject
We present our case report using a novel metal artefact reduction magnetic resonance imaging (MRI) sequence to observe resolution of subchondral bone marrow lesions (BMLs), which are strongly associated with pain, in a patient after total knee replacement surgery. Large BMLs were seen preoperatively on the 3-Tesla MRI scans in a patient with severe end stage OA awaiting total knee replacement surgery. Twelve months after surgery, using a novel metal artefact reduction MRI sequence, we were able to visualize the bone-prosthesis interface and found complete resection and resolution of these BMLs. This is the first reported study in the UK to use this metal artefact reduction MRI sequence at 3-Tesla showing that resection and resolution of BMLs in this patient were associated with an improvement of pain and function after total knee replacement surgery. In this case it was associated with a clinically significant improvement of pain and function after surgery. Failure to eradicate these lesions may be a cause of persistent postoperative pain that is seen in up to 20% of patients following TKR surgery.
  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

    • [1] T. Neogi, “eTh epidemiology and impact of pain in osteoarthritis,” Osteoarthritis and Cartilage, vol. 21, no. 9, pp. 1145-1153, 2013.
    • [2] F. W. Roemer, R. Frobell, D. J. Hunter et al., “MRI-detected subchondral bone marrow signal alterations of the knee joint: terminology, imaging appearance, relevance and radiological diefrential diagnosis,” Osteoarthritis and Cartilage, vol. 17, no. 9, pp. 1115-1131, 2009.
    • [3] A. J. Barr, T. M. Campbell, D. Hopkinson, S. R. Kingsbury, M. A. Bowes, and P. G. Conaghan, “A systematic review of the relationship between subchondral bone features, pain and structural pathology in peripheral joint osteoarthritis,” Arthritis Research & eThrapy , vol. 17, no. 1, article 228, 2015.
    • [4] Y. Zhang, M. Nevitt, J. Niu et al., “Fluctuation of knee pain and changes in bone marrow lesions, efusions, and synovitis on magnetic resonance imaging,” Arthritis & Rheumatism, vol. 63, no. 3, pp. 691-699, 2011.
    • [5] M. J. Dunbar and F. S. Haddad, “Patient satisfaction aeftr total knee replacement,” Bone & Joint Journal, vol. 96, no. 10, pp. 1285-1286, 2014.
    • [6] J. P. Dillenseger, S. Molie`re, P. Choquet, C. Goetz, M. Ehlinger, and G. Bierry, “An illustrative review to understand and manage metal-induced artifacts in musculoskeletal MRI: a primer and updates,” Skeletal Radiology, vol. 45, no. 5, pp. 677-688, 2016.
    • ology Volume 2014 Journal of Hindawi Publishing Corporation ht p:/ www.hindawi.com
  • Inferred research data

    The results below are discovered through our pilot algorithms. Let us know how we are doing!

    Title Trust
  • No similar publications.