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Kitchener, HC; Blanks, R; Cubie, H; Desai, M; Dunn, G; Legood, R; Gray, A; Sadique, Z; Moss, S; MAVARIC Trial Study Group, (2011)
Publisher: NIHR Health Technology Assessment Programme
Languages: English
Types: Article
Subjects:

Classified by OpenAIRE into

mesheuropmc: equipment and supplies, fluids and secretions, bacterial infections and mycoses
Identifiers:doi:10.3310/hta15030
The principal objective was to compare automation-assisted reading of cervical cytology with manual reading using the histological end point of cervical intraepithelial neoplasia grade II (CIN2) or worse (CIN2+). Secondary objectives included (i) an assessment of the slide ranking facility of the Becton Dickinson (BD) FocalPoint™ Slide Profiler (Becton Dickinson, Franklin Lakes, NJ, USA), especially 'No Further Review', (ii) a comparison of the two approved automated systems, the ThinPrep® Imaging System (Hologic, Bedford, MA, USA) and the BD FocalPoint Guided Screener Imaging System, and (iii) automated versus manual in terms of productivity and cost-effectiveness.
  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

    • 1. Lee JSJ, Kuan L, Seho Oh, Patten FW, Wilbur DC. A feasibility study of the AutoPap system location-guided screening. Acta Cytol 1998;42:221-5.
    • 2. Alasio LM, Alphandery C, Grassi P, Ruggeri M, De Palo G, Pilotti S. Performance of the AutoPap primary screening system in the detection of high-risk cases in cervicovaginal smears. Acta Cytol 2001;45:704-8.
    • 3. Cleary J, Rabbitte L, Kenny B, Bennani F, Fitzpatrick B. Impact of FocalPsolindte profiler on reporting of results. IACC meeting, 16-17 May 2003, Sligo, Ireland.
    • 5. Arbyn M, Buntinx F, Van Ranst M, Paraskevardis E, Martin-Hirsch P, Dillner J. Virologic vs cytologic triage of women with equivocal pap smears: a meta analysis of the accuracy to detect high grade intraepithelial neoplasia. J Natl Cancer Inst 2004;96:280-93.
    • 6. Cuzick J, Szarewski A, Cubie H, Hulman G, Kitchener H, Luesley D, et al. Management of women who test positive for high-risk types of human papillomavirus: the HART Study. Lancet 2003;362:1871-6.
    • 7. Manos MM, Kinney WK, Hurley LB, Sherman ME, Shieh-Ngai J, Kurman RJ, et al. Identifying women with cervical neoplasia: using HPV DNA testing for equivocal Papanicolaou results. JAMA 1999;281:1605-10.
    • 8. Solomon D, Schifman M, Tarone R, for the ALTS Group. Comparison of three management strategies for patients with atypical squamous cells of undetermined significance: baseline results from a randomised trial. J Natl Cancer Inst 2001;93:293-9.
    • 9. Pepe MS. eTh statistical evaluation of medical tests for classicfiation and prediction Oxford University Press; 2002.
    • 10. Alonzo TA, Pepe MS, Moskowitz CS. Sample size calculations for comparative studies of medical tests for detecting presence of disease. Stat Med 2002;21:835-52.
    • 11. Dunn G. Statistical evaluation of measurement errors. 2nd edn. London: Arnold; 2004.
    • 12. Moss S, Gray A, Legood R, Henstock E. Evaluation of HPV/LBC cervical screening pilot studies. First report to the Department of Health on evaluation of LBC. Sutton: Cancer Screening Evaluation Unit, Institute of Cancer Research; 2003.
    • 13. Helms LJ, Melnikow J. Determining costs of health care services for cost eefctiveness analysis. eTh case of cervical cancer prevention and treatment. Med Care 1999;7:652-61.
    • 14. Myers ER, McCrory DC, Nanda K, Bastian L, Matchar DB. Mathematical model for the natural history of human papillomavirus infection and cervical carcinogenesis. Am J Epidemiol 2000;151:1158-69.
  • No related research data.
  • Discovered through pilot similarity algorithms. Send us your feedback.

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