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Fisher, J; Ingham, E; Jones, G; Fermor, H; Hasan, J (2013)
Languages: English
Types: Other
Subjects:
A product for use as an implant includes a decellularised natural multi-composite bone transplant material 5. It is decellularised by 90-100% of the cells. The product may be derived from allogeneic or xenogeneic tissue, specifically porcine tissue and may be a ligament, meniscus or enthesis. A method of forming the product is also described and involves freezing and thawing; the use of a fluid jet; incubating in a hypotonic solution with an anionic detergent; washing with hypotonic or isotonic washes; the use of nuclease enzyme and an oxidising agent.
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