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Molla, M.M.; Paul, M.C. (2009)
Languages: English
Types: Other
Subjects: T1, R1

Classified by OpenAIRE into

arxiv: Physics::Fluid Dynamics, Quantitative Biology::Tissues and Organs
Large Eddy Simulation (LES) is performed to study the physiological pulsatile transition to turbulent non-Newtonian blood flow through a 3D model of arterial stenosis using the different non-Newtonian blood viscosity models. The computational domain has been chosen is a simple channel with a biological type stenosis formed eccentrically on the top wall. The physiological pulsation is generated at the inlet of the model using the fourth harmonic of the Fourier series of the physiological pressure pulse (Womersley [1]). The computational results are presented in terms of the post-stenotic re-circulation\ud zone, shear stress, mean and turbulent kinetic energy.
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    • [1] J. R. Womersley, Method for the calculation of velocity, rate of flow and viscous drag in arteries when the pressure gradient is known, J. Physiology, 155 (1955) 553-563.
    • [2] Y. C. Fung, Biomechanics: Circulation, 2nd edition, Springer,1997.
    • [3] S. A. Berger, L.-D. Jou, Flows in stenotic vessels, Annu. Rev. Fluid Mech., 32 (2000) 347-382.
    • [4] C. R. Huang, W. D. Pan, H. W. Chen, A. L. Copley, Thixotropic properties of whole blood from healty human subjects, Biorheology , 24 (1987) 795-801.
    • [5] C. Tu, M. Delville, Pulsatile flow of non-Newtonian fluids through arterial stenosis, J. Biomechanics, 29 (7) (1996) 899-908.
    • [6] J. R. B. Jr, C. Kleinstreuer, J. K. Comer, Rheological effects on pulsatile hemodynamics in a stenose tube., Computers and Fluids, 29 (2000) 695-724.
    • [7] P. Neofytou, D. Drikakis, Effects of blood models on flows through a stenosis, Int. J. Numer. Meth. Fluids, 43 (2003) 597-635.
    • [8] J. Hron, J. Malek, S. Turek, A numerical investigation of flows shear-thinning fluids with applications to blood rheology, Int. J. Numerical Methods in Fluids , 32 (2000) 863-879.
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