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Trivedi, Vivek; Bhomia, Ruchir; Mitchell, John (2014)
Languages: English
Types: Unknown
In this study a solid core drug delivery system (SCDDS) is prepared with silica as a model core, fatty acid as a shell material and supercritical fluid technology as the process. SCDDS can be developed as targeted delivery systems or as sustained/controlled release platforms. SCDDS are coated with fatty acids using supercritical fluid technology (SCFT), allowing the creation of nano-particulate and micro-particulate delivery systems. The operating conditions of low temperature and pressure used to formulate these systems make it attractive for pharmaceutical research, especially for thermo-labile or sensitive bio-materials.
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