Remember Me
Or use your Academic/Social account:


Or use your Academic/Social account:


You have just completed your registration at OpenAire.

Before you can login to the site, you will need to activate your account. An e-mail will be sent to you with the proper instructions.


Please note that this site is currently undergoing Beta testing.
Any new content you create is not guaranteed to be present to the final version of the site upon release.

Thank you for your patience,
OpenAire Dev Team.

Close This Message


Verify Password:
Verify E-mail:
*All Fields Are Required.
Please Verify You Are Human:
fbtwitterlinkedinvimeoflicker grey 14rssslideshare1
Zhang, X; Tang, Sanyi; Cheke, Robert (2015)
Publisher: Elsevier
Languages: English
Types: Article
Subjects: QA

Classified by OpenAIRE into

mesheuropmc: parasitic diseases
Dengue fever is increasing in importance in the tropics and subtropics. Endosymbiotic Wolbachia bacteria as novel control methods can reduce the ability of virus transmission. So, many mosquitoes infected with Wolbachia are released in some countries so that strategies for population replacement can be fulfilled. However, not all of these field trails are successful, for example, releases on Tri Nguyen Island, Vietnam in 2013 failed. Thus, we evaluated a series of relevant issues such as (a) why do some releases fail? (b) What affects the success of population replacement? And (c) Whether or not augmentation can block the dengue diseases in field trials. If not, how we can success be achieved? Models with and without augmentation, incorporating the effects of cytoplasmic incompatibility (CI) and fitness effects are proposed to describe the spread of Wolbachia in mosquito populations. Stability analysis revealed that backward bifurcations and multiple attractors may exist, which indicate that initial quantities of infected and uninfected mosquitoes, augmentation methods (timing, quantity, order and frequency) may affect the success of the strategies. The results show that successful population replacement will rely on selection of suitable strains of Wolbachia and careful design of augmentation methods.
  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

    • [17] H. Laven, Eradication of Culex pipiens fatigNansthrough cytoplasmic incompatibility, Nature 216 (1967) 383.
    • [23] P.G. Schofield, Spatially explicit models of Turelli-Hoffmann Wolbachia invasive wave fronts, J. Theor. Biol. 215 (2002) 121.
    • [24] M.G. Grech, F. Luduen˜a-Almeida, W.R. Almiro´n, Bionomics of Aedes aegypti subpopulations (Diptera: Culicidae) from Argentina, J. Vector Ecol. 35 (2010) 277.
    • [34] X.H. Zhang, S.Y. Tang, R.A. Cheke, Birth-pulse models of Wolbachiainduced cytoplasmic incompatibility in mosquitoes for dengue virus control, Nonlinear Anal-Real. 35 (2015) 236.
  • No related research data.
  • No similar publications.

Share - Bookmark

Cite this article