LOGIN TO YOUR ACCOUNT

Username
Password
Remember Me
Or use your Academic/Social account:

CREATE AN ACCOUNT

Or use your Academic/Social account:

Congratulations!

You have just completed your registration at OpenAire.

Before you can login to the site, you will need to activate your account. An e-mail will be sent to you with the proper instructions.

Important!

Please note that this site is currently undergoing Beta testing.
Any new content you create is not guaranteed to be present to the final version of the site upon release.

Thank you for your patience,
OpenAire Dev Team.

Close This Message

CREATE AN ACCOUNT

Name:
Username:
Password:
Verify Password:
E-mail:
Verify E-mail:
*All Fields Are Required.
Please Verify You Are Human:
fbtwitterlinkedinvimeoflicker grey 14rssslideshare1
Riby, LM; Law, AS; Mclaughlin, J; Murray, J
Publisher: Elsevier
Languages: English
Types: Article
Subjects: RC0321
Previous research has found that the ingestion of glucose boosts task performance in the memory domain (including tasks tapping episodic, semantic and working memory). The present pilot study tested the hypothesis that glucose ingestion would enhance performance on a test of prospective memory. In a between subjects design, 56 adults ranging from 17-80 years of age performed a computerized prospective memory task and an attention (filler) task after 25g of glucose or a sweetness matched placebo. Blood glucose measurements were also taken to assess the impact of individual differences on glucose regulation. After the drink containing glucose, cognitive facilitation was observed on the prospective memory task after excluding subjects with impaired fasting glucose level. Specifically, subjects receiving glucose were 19% more accurate than subjects receiving a placebo, a trend that was marginally non-significant, F(1,41)=3.4, p=0.07 but that had a medium effect size, d=0.58. Subjects receiving glucose were also significantly faster on the prospective memory task, F(1,35) = 4.8, p<0.05, d = 0.6. In addition, elevated baseline blood glucose (indicative of poor glucose regulation) was associated with slower prospective memory responding, F(1, 35) = 4.4, p<0.05, d = 0.57. These data add to the growing body of evidence suggesting that both memory and executive functioning can benefit from the increased provision of glucose to the brain. \ud \ud \ud KEYWORDS: Carbohydrates, Glucose, Glucose Regulation, Cognition, Mental Performance, Prospective Memory
  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

    • 1. Foster JK, Lidder PG, Sünram S. Glucose and memory: fractionation of enhancement effects? Psychopharmacology 1998; 137: 259-270.
    • 2. Kennedy DO, Scholey AB. Glucose administration, heart rate and cognitive performance: effects of increasing mental effort. Psychopharmacology 2000; 149: 63- 71.
    • 3. Meikle A, Riby LM, Stollery B. The impact of glucose ingestion and gluco-regulatory control on cognitive performance: a comparison of younger and middle aged adults. Hum Psychopharmacol 2004; 19: 523-35.
    • 4. Riby LM, McLaughlin J, Riby DM, Graham C. Lifestyle, glucose regulation and the cognitive effects of glucose load in middle-aged adults. Br J Nutr 2008; 100: 1128- 1134.
    • 5. Manning CA, Parsons MW, Gold PE. Anterograde and retrograde enhancement of 24- h memory by glucose in elderly humans. Behav Neural Biol 1992; 5: 125-30.
    • 6. Riby LM, Meikle A, Glover C. The effects of age, glucose ingestion and glucoregulatory control on episodic memory. Age Ageing 2004; 33: 483-487.
    • 7. Riby LM, Marriott A, Bullock R, Hancock J, Smallwood J, McLaughlin J. The Effects of glucose ingestion and glucose regulation on memory performance in older adults with Mild Cognitive Impairment. Eur J Clin Nutr 2009; 63: 566-571.
    • 8. Manning CA, Ragozzino ME, Gold PE. Glucose enhancement of memory in patients with probable senile dementia of the Alzheimer's type. Neurobiol Aging 1993; 14: 523-528.
    • 9. Gradman TJ, Laws A, Thompson LW, Reaven GM. Verbal learning and/or memory improves with glycemic control in older subjects with non-insulin-dependent diabetes mellitus. J Am Geriatr Soc. 1993; 41: 1305-12.
    • 10. McNay EC, Fries TM, Gold PE. Decreases in rat extracellular hippocampal glucose concentration associated with cognitive demand during a spatial task. Proc Nat Acad Sci USA 2000; 97; 2881-2885.
    • 11. Scholey AB, Harper S, Kennedy DO. Cognitive demand and blood glucose. Physiol and Behav 2001; 73, 585-592.
    • 12. Smith MA, Riby LM, van Eekelen JA & Foster JK. Glucose enhancement of human memory: A comprehensive review of the glucose facilitation effect. Neurosci Biobehav Rev. 2011; 35, 770-783.
    • 13. Brandimonte M, Einstein GO, McDaniel MA. Prospective memory: Theory and applications. Mahwah, NJ: Erlbaum; 1996.
    • 14. Riby LM. The impact of age and task domain on cognitive performance: a metaanalytic review of the glucose facilitation effect. Brain Impair 2004; 5: 145-165.
    • 15. Awad N, Gagnon M, Desrochers A, Tsiakas M, Messier C. Impact of peripheral glucoregulation on memory. Behav Neurosci 2002; 116: 691-702.
    • 16. Kaplan RJ, Greenwood CE, Winocur G, Wolever TMS. Cognitive performance is associated with glucose regulation in healthy elderly persons and can be enhanced with glucose and dietary carbohydrates. Am J Clin Nutr 2000; 72: 825-836.
    • 17. Frayn KN. Metabolic regulation: A human perspective. Oxford: Wiley-Blackwell,; 2010.
    • 18. Parker PY, Benton D. Blood-glucose levels selectively influence memory for word lists dichotically presented to the right ear. Neuropsychologia 1995; 33; 843-854.
    • 19. Mark V, Rose FG. Hypoglycaemia. Oxford: Blackwell Scientific; 1981.
    • 20. Sünram-Lea SI, Dewhurst SA, Foster JK. The effect of glucose administration on the recollection and familiarity components of recognition memory. Biol Psychol 2008; 77: 69-75.
    • 21. Riby LM, Riby DM. Glucose, ageing and cognition: The hippocampus hypothesis. Edited by Ballesteros S: Age, Cognition and Neuroscience 2006; Madrid: UNED, Varia 2004, 79-92.
    • 22. Benton D, Owens DS, Parker PY. Blood-glucose influences memory and attention in young-adults. Neuropsychologia 1994; 32: 595-607.
    • 23. Owen L, Finnegan Y, Hu H, Scholey AB, Sünram-Lea SI. Glucose effects on longterm memory performance: duration and domain specificity. Psychopharmacology 2010; 211: 131-40.
    • 24. Messier C, Gagnon M, Knott V. Effect of glucose and peripheral glucose regulation on memory in the elderly. Neurobiol Aging 1997; 18: 297-304.
    • 25. Scholey AB, Sünram-Lea SI, Greer J, Elliott J, Kennedy DO. Glucose administration prior to a divided attention task improves tracking performance but not word recognition: evidence against differential memory enhancement? Psychopharmacology 2009; 202: 549-58.
    • 26. Scholey AB, Harper S, Kennedy DO. Cognitive demand and blood glucose. Physio Behav 2001; 73: 585-592.
    • 27. Sunram-Lea SI, Foster JK, Durlach P, Perez C. Investigation into the significance of task difficulty and divided allocation of resources on the glucose memory facilitation effect. Psychopharmacology 2002; 160: 387-397.
    • 28. Meikle A. Glucose and memory: towards a condition based hypothesis. PhD Thesis 2002, Univer of Bristol.
    • 39. Riby LM, Meikle A, Glover C. The effects of age, glucose ingestion and glucoregulatory control on episodic memory. Age Ageing 2004; 33: 483-487.
    • 40. Meikle A, Riby LM, Stollery B. The impact of glucose ingestion and glucoregulatory control on cognitive performance: A comparison of younger and middleaged adults. Hum Psychopharmacol 2004; 19: 523-535.
    • 41. Smith G, Della Sala S, Logie RH, Maylor EA. Prospective and retrospective memory in normal ageing and dementia: a questionnaire study. Memory 2000; 8: 311-21.
    • 42. Carlesimo GA, Casadio P, Caltagirone C. Prospective and retrospective components in the memory for actions to be performed in patients with closed-head injury. J Int Neuropsychol Soc 2004; 10: 679-88.
    • 43. Burgess PW, Shallice T. The relationship between prospective and retrospective memory: neuropsychological evidence. In: Conway MA, editor. Cognitive Models of Memory. Hove: Psychology Press; 1997. p. 247-272.
    • 44. Allen JB, Gross AM, Aloia MS, Billingsley C. The effects of glucose on nonmemory cognitive functioning in the elderly. Neuropsychologia 1996; 34: 459-465.
    • 45. Smith RE, Hunt RR, McVay JC, McConnell MD. The cost of remembering eventbased prospective memory: Salient target events. J Exp Psychol Learn Mem Cogn 2007; 33: 734-746.
    • 46. Einstein GO, McDaniel MA. Prospective memory and what costs do not reveal about retrieval processes: A commentary on Smith, Hunt, McVay, and McConnell (2007). J Exp Psychol Learn Mem Cogn 2010; 36: 1082-1088.
    • 15 mins
  • No related research data.
  • No similar publications.

Share - Bookmark

Cite this article