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fbtwitterlinkedinvimeoflicker grey 14rssslideshare1
Hendry, Emma; Conway, Barbara; Worthington, Tony (2012)
Publisher: Molecular Diversity Preservation International (MDPI)
Journal: International Journal of Molecular Sciences
Languages: English
Types: Article
Subjects: surface disinfection, Chemistry, healthcare associated infection, chlorhexidine digluconate, QD1-999, biofilm, RM, eucalyptus oil, green biocide, Biology (General), Article, QH301-705.5
Effective surface disinfection is a fundamental infection control strategy within healthcare. This study assessed the antimicrobial efficacy of novel biocide formulations comprising 5% and 2% eucalyptus oil (EO) combined with 2% chlorhexidine digluconate (CHG) and 70% isopropyl alcohol (IPA) contained within a wipe. The efficacy of this novel antimicrobial formulation to remove and eliminate methicillin-resistant Staphylococcus aureus (MRSA), Escherichia coli and Candida albicans from steel surfaces was investigated. Adpression studies of pre-contaminated wipes were also utilised to assess their potential to induce cross-contamination between hard surfaces. Furthermore, the bactericidal nature of the EO-formulation was established in addition to time-kill. The EO-containing formulations demonstrated bactericidal antimicrobial efficacy against all microorganisms and did not induce surface cross-contamination. There was no significant difference (p < 0.05) between the 5% and 2% EO formulations in their ability to remove microorganisms from steel surfaces, however both significantly (p < 0.05) removed more than the control formulations. Microbial biofilms were eliminated within 10 min (p < 0.05) when exposed to the EO formulations. Our novel EO-formulation demonstrated rapid antimicrobial efficacy for potential disinfection and elimination of microbial biofilms from hard surfaces and may therefore be a useful adjunct to current infection control strategies currently employed within healthcare facilities.
  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

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    • 15. Bartz, S.; Ritter, A.C.; Tondo, E.C. Evaluation of bacterial multiplication in cleaning cloths containing different quantities of organic matter. J. Infect. Dev. Countries 2010, 4, 566-571.
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    • 20. Miles, A.A.; Misra, S.S. The estimation of the bactericidal power of the blood. J. Hyg. 1938, 38, 732-749.
  • No related research data.
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