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fbtwitterlinkedinvimeoflicker grey 14rssslideshare1
Blackhall, K; Appleton, S; Cates, CJ (2003)
Publisher: Cochrane Collaboration
Languages: English
Types: Article
Subjects:
: Previous reports have shown that ion content in the air may have an effect on respiratory function. Results from studies which test the efficacy of air ionisers to reduce asthma symptoms are often inconclusive and their use as a treatment for asthma remains debatable.
: We conducted a systematic review of the available evidence to determine the effectiveness of positive and negative ion generators in people with asthma.
: We searched the Cochrane Airways Group Asthma trials register (January 1966 to March 2003), Cochrane Central Register of Controlled Trials (Cochrane Library issue 2, 2003) as well as The Alternative Medicine Database AMED (1985 to March 2003).
: Randomised controlled trials (parallel or crossover design studies) comparing ionisers with dummy ionisers (being negative or positive ion emitters), in children or adults with chronic asthma.
: Two reviewers independently assessed titles and abstracts of studies and assessed trial quality. Study quality was determined using two methods:The Cochrane approach to allocation concealment and the five point Jadad scale.
: Six studies were selected for inclusion (106 participants). No results were combined as the studies were all of a crossover design. EFFECTS OF NEGATIVE ION GENERATORS (five studies)No study reported a significant difference in lung function between ionised and control air (morning Peak expiratory flow (PEF) - three studies; forced expiratory flow in one second (FEV1) - one study). There were no significant differences in symptoms or beta-2 agonist usage between ionised and control air in three studies. EFFECTS OF POSITIVE ION GENERATORS (one study)This study demonstrated that although positively ionised air was associated with a larger fall in FEV1 with exercise, this did not reach statistical significance. Baseline FEV1 was not demonstrated to be significantly different between treatment groups.
: Based on the evidence currently available from randomised controlled trials, a recommendation cannot be given for the use of room air ionisers to reduce symptoms in patients with chronic asthma.
  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

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    • Warner 1993 {published data only} ∗ Warner JA, Marchant JL, Warner JO. Double blind trial of ionisers in children with asthma sensitive to the house dust mite. Thorax 1993;48(4):330-3.
    • Jones 1976 {published data only} Jones DP, O'Connor SA, Collins JV, Watson BW. Effect of long-term ionized air treatment on patients with bronchial asthma. Thorax 1976;31(4):428-32.
    • Kirkham 1984 {published data only} Kirkham AJ, Hawkins L, Guyatt AR, Lumley K, Horsfield K, Cumming G. The effect of air ionisation on lung function in chronic asthmatics. Clinical Science 1984;67 (Suppl 9):62-3.
    • Mitchell 1980 {published data only} Mitchell EA, Elliott RB. Controlled trial of an electrostatic precipitator in childhood asthma. Lancet 1980;2(8194): 559-61.
    • Nogrady 1983b {published data only} Nogrady S, Furnass B, Stevens D. Air ionisation-its effects in bronchial asthma. Australia and New Zealand Journal of Medicine 1983;13(5):547.
    • Osterballe 1979 {published data only} Osterballe O, Weeke B, Albrechtsen O. Influence of small atmospheric ions on the airways in patients with bronchial asthma. Allergy 1979;34(3):187-94.
    • Palti 1966 {published data only} Palti Y, De Nour E, Abrahamov A. The effect of atmospheric ions on the respiratory system of infants. Pediatrics 1966;38 (3):405-11.
    • Ponomarenko 2003 {published data only} ∗ Ponomarenko GN, Ponomareva EV, Sereda VP. Biocontrolled aeroionotherapy - a new method of treatment in patients with bronchial asthma [Bioupravliaemaia aeroionoterapiia - novyi metod lecheniia bol'nykh bronkhial'noi astmoi]. Vopr Kurortol Fizioter Lech Fiz Kult 2003;5:17-9.
    • Wickman 1989 {published data only} Wickman M, Sandvik L, Aas K. Ion generators are not a complement to asthma treatment in children [Jongeneratorer inget komplement i astmabehandlingen hos barn]. Lakartidningen 1989;86(20):1889-90.
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    • Jadad 1996 Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJM, Gavaghan GJ, et al.Assessing the quality of reports of randomised trials: is blinding necessary?. Controlled Clinical Trials 1996;17:1-12.
    • Jonassen 1996 Jonassen N. Ion generators and bronchial asthma [Iongeneratorer og asthma bronchiale]. Ugeskrift for Laeger 1996;158(29):4203-5.
    • ONS 1996 Office for National Statistics, Government Statistical Service. Key health statistics from general practice. Studies on medical and population subjects; No. 60. 1996.
    • Podleski 1980 Podleski WK. Asthma and ionisation. Lancet 1980;2(8202): 1035.
    • Posse 1975 Posse P. Effect of weather on morbidity dynamics in a large city. An investigation on the population of Munich. Munchener Medizinische Wochenschrift 1975;117:425-30.
    • Smith 2000 Smith NM [on behalf of the National Asthma Campaign]. The 'needs of people with asthma' survey and initial presentation of the data. Asthma Journal 2000;5:133-7.
    • Sulman 1984 Sulman FG. The impact of weather on human health. Reviews on Environmental Health 1984;4:83-119.
    • Wagner 1983 Wagner CJ, Danziger RE, Nelson HS. Relation between positive small air ions, weather fronts and pulmonary function in patients with bronchial asthma. Annals of Allergy 1983;51:430-5.
    • Wehner 1969 Wehner AP. Electro-aerosols, air ions and physical medicine. American Journal of Physical Medicine 1969;48(3):119-49.
    • O F A N D Analysis 1.8.
  • No related research data.
  • No similar publications.

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