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Marshall, A. P.; Weisbrodt, L.; Rose, L.; Duncan, E. M.; Prior, M. E.; Todd, L.; Wells, E. C.; Seppelt, I.; Cuthbertson, B. H.; Francis, J. (2014)
Languages: English
Types: Article
Subjects: RC

Classified by OpenAIRE into

mesheuropmc: musculoskeletal diseases
Objective: To describe factors senior critical care nurses identify as being important to address when introducing selective digestive tract decontamination (SDD) in the clinical setting.\ud \ud Background: Critically ill patients are at risk of developing ventilator-associated pneumonia (VAP). SDD is one strategy shown to prevent VAP and possibly improve survival in the critically ill.\ud \ud Methods: We performed a secondary analysis of qualitative data obtained from 20 interviews. An inductive thematic analysis approach was applied to data obtained from senior critical care nurses during phase two of a multi-methods study.\ud \ud Results: There were four primary considerations identified that should be addressed or considered prior to implementation of SDD. These considerations included education of health care professionals, patient comfort, compatibility of SDD with existing practices, and cost.\ud \ud Conclusions: Despite a lack of experience with, or knowledge of SDD, nurses were able to articulate factors that may influence its implementation and delivery. Organizations or researchers considering implementation of SDD should include nurses as key members of the implementation team.
  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

    • American Thoracic Society and Infectious Diseases Society of America 2005. Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. American Journal of Respiratory and Critical Care Medicine 171 (4), 388-416.
    • Barends, H., Zandstra, D.F., vand der Voort, P.H., 2008. Current state of affairs: SDD application in Dutch ICUs. The Netherlands Journal of Critical Care 12, 109-112.
    • Barret, J.P., Jeschke, M.G., Herndon, D.N., 2001. Selective decontamination of the digestive tract in severely burned pediatric patients. Burns 27 (5), 439-445.
    • Bastin, A.J., Ryanna, K.B., 2009. Use of selective decontamination of the digestive tract in United Kingdom intensive care units. Anaesthesia 64 (1), 46-49.
    • Cuthbertson, B.H., Francis, J., Campbell, M.K., MacIntyre, L., Seppelt, I., Grimshaw, J., 2010. A study of the perceived risks, benefits and barriers to the use of SDD in adult critical care units (the SuDDICU study). Trials 11, 117.
    • de Smet, A.M., Kluytmans, J.A., Cooper, B.S., Mascini, E.M., Benus, R.F., van der Werf, T.S., van der Hoeven, J.G., Pickkers, P., Bogaers-Hofman, D., van der Meer, N.J., Bernards, A.T., Kuijper, E.J., Joore, J.C., Leverstein-van Hall, M.A., Bindels, A.J., Jansz, A.R., Wesselink, R.M., de Jongh, B.M., Dennesen, P.J., van Asselt, G.J., te Velde, L.F., Frenay, I.H., Kaasjager, K., Bosch, F.H., van Iterson, M., Thijsen, S.F., Kluge, G.H., Pauw, W., de Vries, J.W., Kaan, J.A., Arends, J.P., Aarts, L.P., Sturm, P.D., Harinck, H.I., Voss, A., Uijtendaal, E.V., Blok, H.E., Thieme Groen, E.S., Pouw, M.E., Kalkman, C.J., Bonten, M.J., 2009. Decontamination of the digestive tract and oropharynx in ICU patients. New England Journal of Medicine 360 (1), 20- 31.
    • Dellinger, R.P., Levy, M.M., Carlet, J.M., Bion, J., Parker, M.M., Jaeschke, R., Reinhart, K., Angus, D.C., Brun-Buisson, C., Beale, R., Calandra, T., Dhainaut, J.F., Gerlach, H., Harvey, M., Marini, J.J., Marshall, J., Ranieri, M., Ramsay, G., Sevransky, J., Thompson, B.T., Townsend, S., Vender, J.S., Zimmerman, J.L., Vincent, J.L., 2008. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Critical Care Medicine 36 (1), 296-327.
    • Doyle, J.S., Buising, K.L., Thursky, K.A., Worth, L.J., Richards, M.J., 2011. Epidemiology of infections acquired in intensive care units. Seminars in Respiratory and Critical Care Medicine 32 (2), 115-138.
    • Feider, L.L., Mitchell, P., Bridges, E., 2010. Oral care practices for orally intubated critically ill adults. American Journal of Critical Care 19 (2), 175-183.
    • Fraga Fuentes, M.D., Garcia Diaz, B., Dde Juana Velasco, P., Bermejo Vicedo, M.T., 1997. Influence of foods on the absorption of antimicrobial agents. Nutrición Hospitalaria 12 (6), 277-288.
    • Hasson, F., Keeney, S., McKenna, H., 2000. Research guidelines for the Delphi survey technique. Journal of Advanced Nursing 32 (4), 1008-1015.
    • Heo, S.M., Haase, E.M., Lesse, A.J., Gill, S.R., Scannapieco, F.A., 2008. Genetic relationships between respiratory pathogens isolated from dental plaque and bronchoalveolar lavage fluid from patients in the intensive care unit undergoing mechanical ventilation. Clinical Infectious Diseases 47 (12), 1562-1570.
    • Hinds, P.S., Vogel, R.J., Clarke-Seffen, L., 1997. The possibilities and pitfalls of doing a secondary analysis of a qualitative data set. Qualitative Health Research 7 (3), 408- 424.
    • Canadian Patient Safety Institute, 2012. Ventilator-associated pneumonia. Safer Healthcare Now! Retrieved 12 December 2012 from http://www.saferhealthcarenow.ca/EN/Interventions/VAP/Pages/default.aspx Edmonton, Alberta.
    • Jongerden, I.P., de Smet, A.M., Kluytmans, J.A., te Velde, L.F., Dennesen, P.J., Wesselink, R.M., Bouw, M.P., Spanjersberg, R., Bogaers-Hofman, D., van der Meer, N.J., de Vries, J.W., Kaasjager, K., van Iterson, M., Kluge, G.H., van der Werf, T.S., Harinck, H.I., Bindels, A.J., Pickkers, P., Bonten, M.J., 2010. Physicians' and nurses' opinions on selective decontamination of the digestive tract and selective oropharyngeal decontamination: a survey. Critical Care 14 (4), R132.
    • Koeman, M., van der Ven, A.J., Hak, E., Joore, H.C., Kaasjager, K., de Smet, A.G., Ramsay, G., Dormans, T.P., Aarts, L.P., de Bel, E.E., Hustinx, W.N., van der Tweel, I., Hoepelman, A.M., Bonten, M.J., 2006. Oral decontamination with chlorhexidine reduces the incidence of ventilator-associated pneumonia. American Journal of Respiratory and Critical Care Medicine 173 (12), 1348-1355.
    • Kollef, M.H., 2000. Opinion: the clinical use of selective digestive decontamination. Critical Care 4 (6), 327-332.
    • Korinek, A.M., Laisne, M.J., Nicolas, M.H., Raskine, L., Deroin, V., Sanson-Lepors, M.J., 1993. Selective decontamination of the digestive tract in neurosurgical intensive care unit patients: a double-blind, randomized, placebo-controlled study. Critical Care Medicine 21 (10), 1466-1473.
    • Labeau, S.O., Van de Vyver, K., Brusselaers, N., Vogelaers, D., Blot, S.I., 2011. Prevention of ventilator-associated pneumonia with oral antiseptics: a systematic review and meta-analysis. Lancet Infectious Diseases 11 (11), 845-854.
    • Liberati, A., D'Amico, R., Pifferi, Torri, V., Brazzi, L., 2004. Antibiotic prophylaxis to reduce respiratory tract infections and mortality in adults receiving intensive care. Cochrane Database of Systematic Reviews (1), CD000022.
    • Masterton, R.G., Galloway, A., French, G., Street, M., Armstrong, J., Brown, E., Cleverley, J., Dilworth, P., Fry, C., Gascoigne, A.D., Knox, A., Nathwani, D., Spencer, R., Wilcox, M., 2008. Guidelines for the management of hospital-acquired pneumonia in the UK: report of the working party on hospital-acquired pneumonia of the British Society for Antimicrobial Chemotherapy. Journal of Antimicrobial Chemotherapy 62 (1), 5-34.
    • Melsen, W.G., de Smet, A.M., Kluytmans, J.A., Bonten, M.J., 2012. Selective decontamination of the oral and digestive tract in surgical versus non-surgical patients in intensive care in a cluster-randomized trial. British Journal of Surgery 99 (2), 232- 237.
    • Michie, S., Johnston, M., Abraham, C., Lawton, R., Parker, D., Walker, A., 2005. Making psychological theory useful for implementing evidence based practice: a consensus approach. Quality and Safety in Health Care 14 (1), 26-33.
    • Miles, M.B., Huberman, A.M., 1994. Qualitative data analysis: An expanded sourcebook. Sage, Thousand Oaks.
    • Misset, B., Artigas, A., Bihari, D., Carlet, J., Durocher, A., Hemmer, M., Langer, M., Nicolas, F., de Rohan-Chabot, P., Schuster, H.P., Tensillon, A., 1996. Short-term impact of the European Consensus Conference on the use of selective decontamination of the digestive tract with antibiotics in ICU patients. Intensive Care Medicine 22 (9), 981-984.
    • Morris, A.C., Hay, A.W., Swann, D.G., Everingham, K., McCulloch, C., McNulty, J., Brooks, O., Laurenson, I.F., Cook, B., Walsh, T.S., 2011. Reducing ventilatorassociated pneumonia in intensive care: impact of implementing a care bundle. Critical Care Medicine 39 (10), 2218-2224.
    • Muscedere, J., Dodek, P., Keenan, S., Fowler, R., Cook, D., Heyland, D., 2008. Comprehensive evidence-based clinical practice guidelines for ventilator-associated pneumonia: diagnosis and treatment. Journal of Critical Care 23 (1), 138-147.
    • Ochoa-Ardila, M.E., Garcia-Canas, A., Gomez-Mediavilla, K., Gonzalez-Torralba, A., Alia, I., Garcia-Hierro, P., Taylor, N., van Saene, H.K., de la Cal, M.A., 2011. Long-term use of selective decontamination of the digestive tract does not increase antibiotic resistance: a 5-year prospective cohort study. Intensive Care Medicine 37 (9), 1458- 1465.
    • Poissy, J., Senneville, E., 2011. New antibiotics for severe ICU-aquired bacterial infections. Infectious Disorders - Drug Targets 11 (4), 401-412.
    • Productivity Commission, 2009. Public and Private Hospitals. Commonwealth of Australia, Canberra, ACT.
    • Rello, J., Lode, H., Cornaglia, G., Masterton, R., 2010. A European care bundle for prevention of ventilator-associated pneumonia. Intensive Care Medicine 36 (5), 773- 780.
    • Richards, M., Thursky, K., Buising, K., 2003. Epidemiology, prevalence, and sites of infections in intensive care units. Semininars in Respiratory and Critical Care Medicine 24 (1), 3-22.
    • Rocha, L.A., Martin, M.J., Pita, S., Paz, J., Seco, C., Margusino, L., Villanueva, R., Duran, M.T., 1992. Prevention of nosocomial infection in critically ill patients by selective decontamination of the digestive tract. A randomized, double blind, placebocontrolled study. Intensive Care Medicine 18 (7), 398-404.
    • Sanchez Garcia, M., Cambronero Galache, J.A., Lopez Diaz, J., Cerdá, C.E., Rubio, B.J., Gómez, A.M.A., Núnez, R.A., Rogero, M.S., Onoro, C.J.J., Sacristán del Castillo, J.A., 1998. Effectiveness and cost of selective decontamination of the digestive tract in critically ill intubated patients. A randomized, double-blind, placebo-controlled, multicenter trial. American Journal of Respiratory and Critical Care Medicine 158, 908-916.
    • Silvestri, L., Petros, A.J., De La Cal, M.A., Visintin, S., 2011. Selective digestive decontamination. Why are intensivists more "resistant" than microorganisms? Minerva Anestesiologica 77 (6), 658-659.
    • Silvestri, L., van Saene, H.K., Milanese, M., Gregori, D., 2005. Impact of selective decontamination of the digestive tract on fungal carriage and infection: systematic review of randomized controlled trials. Intensive Care Medicine 31 (7), 898-910.
    • Silvestri, L., van Saene, H.K., Petros, A.J., 2012. Selective digestive tract decontamination in critically ill patients. Expert Opinions in Pharmacotherapy 13 (8), 1113-1129.
    • Silvestri, L., van Saene, H.K.F., 2012. Selective decontamination of the digestive tract: an update of the evidence. HSR Proceedings in Intensive Care and Cardiovascular Anesthesia 4 (1), 21-29.
    • Smit, M.J., van der Spoel, J.I., de Smet, A.M., de Jonge, E., Kuiper, R.A., van Lieshout, E.J., 2007. Accumulation of oral antibiotics as an adverse effect of selective decontamination of the digestive tract: a series of three cases. Intensive Care Medicine 33 (11), 2025-2026.
    • Stoutenbeek, C.P., van Saene, H.K.F., Zandstra, D.F., 1996. Prevention of multiple organ failure by selective decontamination of the digestive tract in multiple trauma patients. In: Faist, E., Baue, A.E., Schildberg, F.W. (Eds.), The Immune Consequences of Trauma, Shock and Sepsis - Mechanisms and Therapeutic Approaches. Pabst Science Publishers, Lengerich, pp. 1055-1066.
    • Thomas, D.R., 2006. An inductive approach for analyzing qualitative evaluation data. American Journal of Evaluation 27 (2), 237-246.
    • Thorne, S., 1998. Ethical and representational issues in qualitative secondary analysis. Qualitative Health Research 8 (4), 547-555.
    • van der Voort, P.H., van Roon, E.N., Kampinga, G.A., Boerma, E.C., Gerritsen, R.T., Egbers, P.H., Kuiper, M.A., 2004. A before-after study of multi-resistance and cost of selective decontamination of the digestive tract. Infection 32 (5), 271-277.
    • van Enckevort, P.J., Zwaveling, J.H., Bottema, J.T., Maring, J.K., Klompmaker, I.J., Slooff, M.J., TenVergert, E.M., 2001. Cost effectiveness of selective decontamination of the digestive tract in liver transplant patients. Pharmacoeconomics 19 (5 Pt 1), 523-530.
    • van Essen, E.H., de Jonge, E., 2011. Selective decontamination of the digestive tract (SDD): is the game worth the candle? Semininars in Respiratory and Critical Care Medicine 32 (2), 236-242.
    • Vandijck, D.M., Labeau, S.O., Vogelaers, D.P., Blot, S.I., 2010. Prevention of nosocomial infections in intensive care patients. Nursing in Critical Care 15 (5), 251-256.
    • Vincent, J.L., Rello, J., Marshall, J., Silva, E., Anzueto, A., Martin, C.D., Moreno, R., Lipman, J., Gomersall, C., Sakr, Y., Reinhart, K., 2009. International study of the prevalence and outcomes of infection in intensive care units. JAMA 302 (21), 2323- 2329.
    • Weinert, C.R., Mann, H.J., 2008. The science of implementation: changing the practice of critical care. Current Opinions in Critical Care 14 (4), 460-465.
    • Wunderink, R.G., 2010. Welkommen to our world. Emergence of antibiotic resistance with selective decontamination of the digestive tract. American Journal of Respiratory and Critical Care Medicine 181 (5), 426-427.
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