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We demonstrate that a non self-adjoint Hamiltonian of harmonic oscillator type defined on a two-dimensional noncommutative space can be diagonalized exactly by making use of pseudo-bosonic operators. The model admits an antilinear symmetry and is of the type studied in the context of PT-symmetric quantum mechanics. Its eigenvalues are computed to be real for the entire range of the coupling constants and the biorthogonal sets of eigenstates for the Hamiltonian and its adjoint are explicitly constructed. We show that despite the fact that these sets are complete and biorthogonal, they involve an unbounded metric operator and therefore do not constitute (Riesz) bases for the Hilbert space $\Lc^2(\Bbb R^2)$, but instead only D-quasi bases. As recently proved by one of us (FB), this is sufficient to deduce several interesting consequences.
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