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Gartland, N; O'Connor, DB; Lawton, R; Bristow, M (2014)
Publisher: Elsevier
Languages: English
Types: Article

Classified by OpenAIRE into

mesheuropmc: human activities
Stress is associated with the secretion of cortisol throughout the day, but less is\ud known about the dynamic effects of stress on the cortisol awakening response (CAR). More widely, knowledge of the causal factors and functions of the CAR are also not fully understood. This study explored: (1) the effects of daily stressors on the next day CAR and; (2) the effects of the CAR on same day physical and affective outcomes. Sixty-four participants completed a daily diary, reporting on the occurrence of daily stressors and stress appraisals, physical symptoms, and affect. Cortisol was measured at 0, 15, 30, and 45 min after awakening to provide measures of the CAR on 3 consecutive work days. Stress appraisal was found to negatively predict the CAR, such that where stressors were appraised as more stressful (where perceived demands exceeded resources), the CAR increased less the following morning. Furthermore, the CAR significantly predicted same-day physical symptoms such that a lower CAR was associated with more physical symptoms. This study provides evidence for a pathway through which daily stressors may influence physical wellbeing, and highlights the importance of appraisals for future stress-based cortisol research.
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    • Adam, E. K., Hawkley, L. C., Kudielka, B. M., & Cacioppo, J. T., 2006. Day-to-day dynamics of experience-cortisol associations in a population-based sample of older adults. Proc. Natl. Acad. Sci. U. S. A., 103, 17058-17063.
    • Almeida, D. M., Piazza, J. R., & Stawski, R. S., 2009. Interindividual Differences and Intraindividual Variability in the Cortisol Awakening Response: An Examination of Age and Gender. Psychol. Aging, 24, 819-827.
    • Bellingrath, S., Weigl, T., & Kudielka, B. M., 2008. Cortisol dysregulation in school teachers in relation to burnout, vital exhaustion, and effort-reward-imbalance. Biol. Psychol., 78, 104- 113.
    • Cleare, A. J., Heap, E., Malhi, G. S., Wessely, S., O'Keane, V., & Miell, J., 1999. Low-dose hydrocortisone in chronic fatigue syndrome: a randomised crossover trial. Lancet, 353, 455- 458.
    • Clow, A., Hucklebridge, F., Stalder, T., Evans, P., & Thorn, L., 2010. The cortisol awakening response: More than a measure of HPA axis function. Neurosci. Biobehav. Rev., 35, 97-103.
    • Clow, A., Thorn, L., Evans, P., & Hucklebridge, F., 2004. The awakening cortisol response: Methodological issues and significance. Stress-the International Journal on the Biology of Stress, 7, 29-37.
    • Dahlgren, A., Kecklund, G., Theorell, T., & Akerstedt, T., 2009. Day-to-day variation in saliva cortisol--relation with sleep, stress and self-rated health. Biol. Psychol., 82, 149-155.
    • Doane, L. D., & Adam, E. K., 2010. Loneliness and cortisol: Momentary, day-to-day, and trait associations. Psychoneuroendocrinology, 35, 430-441.
    • Ferguson, E., 2008. Health anxiety moderates the daytime cortisol slope. J. Psychosom. Res., 64, 487- 494.
    • Ferguson, E., Cassaday, H. J., Erskind, J., & Delahaye, G., 2004. Individual differences in the temporal variability of medically unexplained symptom reporting. British Journal of Health Psychology, 9, 219-240.
    • Fries, E., Dettenborn, L., & Kirschbaum, C., 2009. The cortisol awakening response (CAR): Facts and future directions. Int. J. Psychophysiol., 72, 67-73.
    • Gaab, J., Rohleder, N., Nater, U. M., & Ehlert, U., 2005. Psychological determinants of the cortisol stress response: the role of anticipatory cognitive appraisal. Psychoneuroendocrinology, 30, 599-610.
    • Gartland, N., O'Connor, D. B., & Lawton, R., 2012. The Effects of Conscientiousness on the Appraisals of Daily Stressors. Stress and Health, 28, 80-86.
    • Gartland, N., O'Connor, D. B., Lawton, R., & Ferguson, E., 2014. Investigating the effects of conscientiousness on daily stress, affect and physical symptom processes: A daily diary study. British Journal of Health Psychology, 19, 311-328.
    • Hellhammer, J., Fries, E., Schweisthal, O. W., Schlotz, W., Stone, A. A., & Hagemann, D., 2007. Several daily measurements are necessary to reliably assess the cortisol rise after awakening: State- and trait components. Psychoneuroendocrinology, 32, 80-86.
    • Jacobs, N., Myin-Germeys, I., Derom, C., Delespaul, P., van Os, J., & Nicolson, N. A., 2007. A momentary assessment study of the relationship between affective and adrenocortical stress responses in daily life. Biol. Psychol., 74, 60-66.
    • Kiecolt-Glaser, J. K., McGuire, L., Robles, T. F., & Glaser, R., 2002. Psychoneuroimmunology: Psychological influences on immune function and health. J. Consult. Clin. Psychol., 70, 537- 547.
    • Kudielka, B. M., Broderick, J. E., & Kirschbaum, C., 2003. Compliance with saliva sampling protocols: Electronic monitoring reveals invalid cortisol daytime profiles in noncompliant subjects. Psychosom. Med., 65, 313-319.
    • Kudielka, B. M., Gierens, A., Hellhammer, D. H., Wust, S., & Schlotz, W., 2012. Salivary Cortisol in Ambulatory Assessment-Some Dos, Some Don'ts, and Some Open Questions. Psychosom. Med., 74, 418-431.
    • Kumari, M., Badrick, E., Chandola, T., Adam, E. K., Stafford, M., Marmot, M. G., et al., 2009. Cortisol secretion and fatigue: Associations in a community based cohort. Psychoneuroendocrinology, 34, 1476-1485.
    • Kunz-Ebrecht, S. R., Kirschbaum, C., Marmot, M., & Steptoe, A., 2004. Differences in cortisol awakening response on work days and weekends in women and men from the Whitehall II cohort. Psychoneuroendocrinology, 29, 516-528.
    • Kupper, N., de Geus, E. J. C., van den Berg, M., Kirschbaum, C., Boomsma, D. I., & Willemsen, G., 2005. Familial influences on basal salivary cortisol in an adult population. Psychoneuroendocrinology, 30, 857-868.
    • Lasikiewicz, N., Hendrickx, H., Talbot, D., & Dye, L., 2008. Exploration of basal diurnal salivary cortisol profiles in middle-aged adults: Associations with sleep quality and metabolic parameters. Psychoneuroendocrinology, 33, 143-151.
    • Law, R., Hucklebridge, F., Thorn, L., Evans, P., & Clow, A., 2013. State variation in the cortisol awakening response. Stress, 16, 483-492.
    • Lazarus, R. S., & Folkman, S. (1984). Stress, appraisal, and coping. New York: Springer Publishing Company.
    • Mackinnon, A., Jorm, A. F., Christensen, H., Korten, A. E., Jacomb, P. A., & Rodgers, B., 1999. A short form of the Positive and Negative Affect Schedule: evaluation of factorial validity and invariance across demographic variables in a community sample. Personality and Individual Differences, 27, 405-416.
    • McKenzie, R., O'Fallon, A., Dale, J., Demitrack, M., Sharma, G., Deloria, M., et al., 1998. Low-dose hydrocortisone for treatment of chronic fatigue syndrome - A randomized controlled trial. Jama-Journal of the American Medical Association, 280, 1061-1066.
    • Miller, G. E., Chen, E., & Zhou, E. S., 2007. If it goes up, must it come down? Chronic stress and the hypothalamic-pituitary-adrenocortical axis in humans. Psychol. Bull., 133, 25-45.
    • O'Connor, D. B., Hendrickx, H., Dadd, T., Elliman, T. D., Willis, T. A., Talbot, D., et al., 2009. Cortisol awakening rise in middle-aged women in relation to psychological stress. Psychoneuroendocrinology, 34, 1486-1494.
    • O'Connor, D. B., Jones, F., Conner, M., McMillan, B., & Ferguson, E., 2008. Effects of daily hassles and eating style on eating behavior. Health Psychol., 27, S20-S31.
    • O'Connor, D. B., Walker, S., Hendrickx, H., Talbot, D., & Schaefer, A., 2013. Stress-related thinking predicts the cortisol awakening response and somatic symptoms in healthy adults. Psychoneuroendocrinology, 38, 438-446.
    • Pressman, S. D., & Cohen, S., 2005. Does positive affect influence health? Psychol. Bull., 131, 925- 971.
    • Pruessner, J. C., Hellhammer, D. H., & Kirschbaum, C., 1999. Burnout, perceived stress, and cortisol responses to awakening. Psychosom. Med., 61, 197-204.
    • Pruessner, J. C., Kirschbaum, C., Meinlschmid, G., & Hellhammer, D. H., 2003. Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change. Psychoneuroendocrinology, 28, 916-931.
    • Pruessner, J. C., Wolf, O. T., Hellhammer, D. H., BuskeKirschbaum, A., vonAuer, K., Jobst, S., et al., 1997. Free cortisol levels after awakening: A reliable biological marker for the assessment of adrenocortical activity. Life Sci., 61, 2539-2549.
    • Raudenbush, S., Bryk, A., Cheong, Y. F., & Congdon, R. (2004). HLM 6: Hierarchical Linear and Nonlinear Modelling. Lincolnwood: Scientific Software International.
    • Raudenbush, S., Bryk, A., Cheong, Y. F., Congdon, R., & du Toit, M. (2011). HLM 7: Hierarchical Linear and Nonlinear Modeling: Scientific Software Internation, Lincolnwood, IL.
    • Schneider, T. R., 2008. Evaluations of stressful transactions: What's in an appraisal? Stress and Health, 24, 151-158.
    • Stalder, T., Evans, P., Hucklebridge, F., & Clow, A., 2010a. Associations between psychosocial state variables and the cortisol awakening response in a single case study. Psychoneuroendocrinology, 35, 209-214.
    • Stalder, T., Evans, P., Hucklebridge, F., & Clow, A., 2010b. State associations with the cortisol awakening response in healthy females. Psychoneuroendocrinology, 35, 1245-1252.
    • Stalder, T., Hucklebridge, F., Evans, P., & Clow, A., 2009. Use of a single case study design to examine state variation in the cortisol awakening response: Relationship with time of awakening. Psychoneuroendocrinology, 34, 607-614.
    • Steptoe, A., Dockray, S., & Wardle, J., 2009. Positive Affect and Psychobiological Processes Relevant to Health. J. Pers., 77, 1747-1776.
    • Thorn, L., Hucklebridge, F., Evans, P., & Clow, A., 2006. Suspected non-adherence and weekend versus week day differences in the awakening cortisol response. Psychoneuroendocrinology, 31, 1009-1018.
    • Thorn, L., Hucklebridge, F., Evans, P., & Clow, A., 2009. The cortisol awakening response, seasonality, stress and arousal: A study of trait and state influences. Psychoneuroendocrinology, 34, 299-306.
    • Tomaka, J., Blascovich, J., Kibler, J., & Ernst, J. M., 1997. Cognitive and physiological antecedents of threat and challenge appraisal. J. Pers. Soc. Psychol., 73, 63-72.
    • van Eck, M., Berkhof, H., Nicolson, N., & Sulon, J., 1996. The effects of perceived stress, traits, mood states, and stressful daily events on salivary cortisol. Psychosom. Med., 58, 447-458.
    • Waye, K. P., Clow, A., Edwards, S., Hucklebridge, F., & Rylander, R., 2003. Effects of nighttime low frequency noise on the cortisol response to awakening and subjective sleep quality. Life Sci., 72, 863-875.
    • Wilson, R. S., Bienias, J. L., de Leon, C. F. M., Evans, D. A., & Bennett, D. A., 2003. Negative affect and mortality in older persons. Am. J. Epidemiol., 158, 827-835.
    • Wirtz, P. H., von Kanel, R., Emini, L., Ruedisueli, K., Groessbauer, S., Maercker, A., et al., 2007. Evidence for altered hypothalamus-pituitary-adrenal axis functioning in systemic hypertension: Blunted cortisol response to awakening and lower negative feedback sensitivity. Psychoneuroendocrinology, 32, 430-436.
    • Table 5. Level 1 effects of CAR AUCi predicting same-day physical symptoms severity and frequency, controlling for prior-day physical symptoms. HLM effect Symbol Coeff SE p CAR AUCi - Severity Intercept 00 16.77 0.67 <.001 Level-1 slopes CAR AUCi Same-day PS 10 -0.23 0.07 0.003 Prior-day PS severity Same-day PS 20 -0.20 0.12 0.11 CAR AUCi - Frequency Intercept 00 2.31 0.25 <.001 Level-1 slopes CAR AUCi Same-day PS 10 -0.07 0.03 0.03 Prior-day PS freq Same-day PS 20 -0.30 0.11 0.01 CAR AUCi cortisol awakening response with respect to increase, PS physical symptoms.
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