LOGIN TO YOUR ACCOUNT

Username
Password
Remember Me
Or use your Academic/Social account:

CREATE AN ACCOUNT

Or use your Academic/Social account:

Congratulations!

You have just completed your registration at OpenAire.

Before you can login to the site, you will need to activate your account. An e-mail will be sent to you with the proper instructions.

Important!

Please note that this site is currently undergoing Beta testing.
Any new content you create is not guaranteed to be present to the final version of the site upon release.

Thank you for your patience,
OpenAire Dev Team.

Close This Message

CREATE AN ACCOUNT

Name:
Username:
Password:
Verify Password:
E-mail:
Verify E-mail:
*All Fields Are Required.
Please Verify You Are Human:
fbtwitterlinkedinvimeoflicker grey 14rssslideshare1
Standley, Claire J; Goodacre, Sara L; Wade, Christopher M; Stothard, J Russell (2014)
Publisher: BioMed Central
Journal: Parasites & Vectors
Languages: English
Types: Article
Subjects: qx_355, Population genetics, qu_470, Population structure, Infectious Diseases, wa_110, wa_395, wc_810, Research, Schistosoma mansoni, Biomphalaria choanomphala, Parasitology

Classified by OpenAIRE into

mesheuropmc: parasitic diseases, fungi
Background The freshwater snail Biomphalaria acts as the intermediate host of Schistosoma mansoni, a globally important human parasite. Understanding the population structure of intermediate host species can elucidate transmission dynamics and assist in developing appropriate control methods. Methods We examined levels of population genetic structure and diversity in 29 populations of Biomphalaria choanomphala collected around the shoreline of Lake Victoria in Uganda, Kenya and Tanzania, where S. mansoni is hyper-endemic. Molecular markers were utilized to estimate the degree to which snail populations are genetically differentiated from one another. Results High levels of snail genetic diversity were found coupled with evidence of geographically-determined population structure but low levels of local inbreeding. The data are consistent with an effect of schistosome infection on population structure of intermediate host snails, but other factors, such as habitat and historical demographic changes, could also be important determinants of the degree of population genetic structure in Biomphalaria choanomphala. Conclusions The low stratification of populations and high genetic diversity indicates potentially less local compatibility with intermediate snail populations than previously theorized, and highlights the importance of coordinated parasite control strategies across the region. Electronic supplementary material The online version of this article (doi:10.1186/s13071-014-0524-4) contains supplementary material, which is available to authorized users.
  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

    • 1. Hoffman JI, Webster JP, Ndamba J, Woolhouse MEJ: Extensive genetic variation revealed in adjacent populations of the schistosome intermediate host Biomphalaria pfeifferi from a single river system. Ann Trop Med Parasitol 1998, 92:693-698.
    • 2. Jarne P, Theron A: Genetic structure in natural populations of flukes and snails: a practical approach and review. Parasitology 2001, 123:S27-S40.
    • 3. Webster JP, Davies CM, Hoffman JI, Ndamba J, Noble LR, Woolhouse MEJ: Population genetics of the schistosome intermediate host Biomphalaria pfeifferi in the Zimbabwean highveld: implications for co-evolutionary theory. Ann Trop Med Parasitol 2001, 95:203-214.
    • 4. Sandland GJ, Foster AV, Zavodna M, Minchella DJ: Interplay between host genetic variation and parasite transmission in the Biomphalaria glabrata Schistosoma mansoni system. Parasitol Res 2007, 101:1083-1089.
    • 5. Sandland GJ, Wethington AR, Foster AV, Minchella DJ: Effects of host outcrossing on the interaction between an aquatic snail and its locally adapted parasite. Parasitol Res 2009, 105:555-561.
    • 6. Webster JP, Woolhouse MEJ: Cost of resistance: relationship between reduced fertility and increased resistance in a snail-schistosome host-parasite system. Proc R Soc B Biol Sci 1999, 266:391-396.
    • 7. Webster JP, Shrivastava J, Johnson PJ, Blair L: Is host-schistosome coevolution going anywhere? BMC Evol Biol 2007, 7:91. doi:10.1186/1471-2148-7-91.
    • 8. Anderson RC: Nematode Parasites of Vertebrates: Their Development and Transmission. Volume 1. Wallingford, UK: CABI; 2000:672.
    • 9. Esteban J-G, Muñoz-Antoli C, Trelis M, Toledo R: Biomphalaria Snails and Larval Trematodes. New York, NY: Springer New York; 2011:127-157.
    • 10. Webster JP, Davies CM, Ndamba J, Noble LR, Jones CS, Woolhouse MEJ: Spatio-temporal genetic variability in the schistosome intermediate host Biomphalaria pfeifferi. Ann Trop Med Parasitol 2001, 95:515-527.
    • 11. Charbonnel N, Angers B, Rasatavonjizay R, Bremond P, Debain C, Jarne P: The influence of mating system, demography, parasites and colonization on the population structure of Biomphalaria pfeifferi in Madagascar. Mol Ecol 2002, 11:2213-2228.
    • 12. Mavárez J, Pointier JP, David P, Delay B, Jarne P: Genetic differentiation, dispersal and mating system in the schistosome-transmitting freshwater snail Biomphalaria glabrata. Heredity (Edinb) 2002, 89:258-265.
    • 13. Lardans V, Dissous C: Snail Control Strategies for Reduction of Schistosomiasis Transmission. Parasitol Today 1998, 14:413-417.
    • 14. Morgan JAT, Dejong RJ, Snyder SD, Mkoji GM, Loker ES: Schistosoma mansoni and Biomphalaria: past history and future trends. Parasitology 2001, 123:S211-S228.
    • 15. Brown D: Freshwater Snails of Africa and Their Medical Importance. 2nd edition. London: Taylor and Francis; 1994.
    • 16. Stothard JR, Webster BL, Weber T, Nyakaana S, Webster JP, Kazibwe F, Kabatereine NB, Rollinson D: Molecular epidemiology of Schistosoma mansoni in Uganda: DNA barcoding reveals substantive genetic diversity within Lake Albert and Lake Victoria populations. Parasitology 2009, 136:1813-1824.
    • 17. Stothard JR, Kabatereine NB, Tukahebwa EM, Kazibwe F, Mathieson W, Webster JP, Fenwick A: Field evaluation of the Meade Readiview handheld microscope for diagnosis of intestinal schistosomiasis in Ugandan school children. Am J Trop Med Hyg 2005, 73:949-955.
    • 18. Standley CJ, Adriko M, Alinaitwe M, Kazibwe F, Kabatereine NB, Stothard JR: Intestinal schistosomiasis and soil-transmitted helminthiasis in Ugandan schoolchildren: a rapid mapping assessment. Geospat Health 2009, 4:39-53.
    • 19. Standley CJ, Kabatereine NB, Lange C, Lwambo NJS, Stothard JR: Molecular epidemiology and phylogeography of Schistosoma mansoni around Lake Victoria. Parasitology 2010, 137:1937-1949.
    • 20. Standley CJ, Wade C, Stothard JR: A fresh insight into the transmission of schistosomiasis: A misleading tale of Biomphalaria in Lake Victoria. PLoS One 2011, 6:e26563.
    • 21. Asch HL: Rhythmic emergence of Schistosoma mansoni cercariae from Biomphalaria glabrata: Control by illumination. Exp Parasitol 1972, 31:350-355.
    • 22. Stothard JR, Rollinson D: Partial DNA sequences from the mitochondrial cytochrome oxidase subunit I (COI) gene can differentiate the intermediate snail hosts Bulinus globosus and B. nasutus (Gastropoda: Planorbidae). J Nat Hist 1997, 31:727-737.
    • 23. Folmer O, Black M, Hoeh W, Lutz R, Vrijenhoek R: DNA primers for amplification of mitochondrial cytochrome c oxidase subunit I from diverse metazoan invertebrates. Mol Mar Biol Biotechnol 1994, 3:294-299.
    • 24. Bonnaud L, Boucher-Rodoni R, Monnerot M: Phylogeny of decapod cephalopods based on partial 16S rDNA nucleotide sequences. C R Acad Sci III 1994, 317:581-588.
    • 25. Charbonnel N, Angers B, Razatavonjizay R, Bremond P, Jarne P: Microsatellite variation in the freshwater snail Biomphalaria pfeifferi. Mol Ecol 2000, 9:1006-1007.
    • 26. Maddison DR, Maddison WP: MacClade 4: Analysis of phylogeny and character evolution. 2005, http://macclade.org/downloads/ReadMe.pdf.
    • 27. Excoffier L, Laval G, Schneider S: Arlequin ver. 3.0: An integrated software package for population genetics data analysis. Evol Bioinform Online 2005, 1:47-50.
    • 28. Swofford DL: PAUP*. Phylogenetic Analysis Using Parsimony (*and other methods). In Version 4. Sunderland, Massachusetts: Sinauer Associates; 2002.
    • 29. Bandelt HJ, Forster P, Röhl A: Median-joining networks for inferring intraspecific phylogenies. Mol Biol Evol 1999, 16:37-48.
    • 30. Raymond M, Rousset F: Genepop (Version-1.2) - Population-Genetics Software for Exact Tests and Ecumenicism. J Hered 1995, 86:248-249.
    • 31. Cornuet JM, Luikart G: Description and power analysis of two tests for detecting recent population bottlenecks from allele frequency data. Genetics 1997, 144:2001-2014.
    • 32. Caldeira RL, Jannotti-Passos LK, Carvalho OS: Molecular epidemiology of Brazilian Biomphalaria: a review of the identification of species and the detection of infected snails. Acta Trop 2009, 111:1-6.
    • 33. Born-Torrijos A, Poulin R, Raga JA, Holzer AS: Estimating trematode prevalence in snail hosts using a single-step duplex PCR: how badly does cercarial shedding underestimate infection rates? Parasit Vectors 2014, 7:243.
    • 34. Ittiprasert W, Miller A, Su X, Mu J, Bhusudsawang G, Ukoskit K, Knight M: Identification and characterisation of functional expressed sequence tags-derived simple sequence repeat (eSSR) markers for genetic linkage mapping of Schistosoma mansoni juvenile resistance and susceptibility loci in Biomphalaria glabrata. Int J Parasitol 2013, 43:669-677.
    • 35. Blouin MS, Bonner KM, Cooper B, Amarasinghe V, O'Donnell RP, Bayne CJ: Three genes involved in the oxidative burst are closely linked in the genome of the snail, Biomphalaria glabrata. Int J Parasitol 2013, 43:51-55.
    • 36. Sire C, Durand P, Pointier JP, Theron A: Genetic diversity of Schistosoma mansoni within and among individual hosts (Rattus rattus): infrapopulation differentiation at microspatial scale. Int J Parasitol 2001, 31:1609-1616.
    • 37. Dybdahl MF, Lively CM: The geography of coevolution: comparative population structures for a snail and its trematode parasite. Evolution (N Y) 1996, 50:2264-2275.
    • 38. Bandoni SM, Mulvey M, Koech DK, Loker ES: Genetic structure of Kenyan populations of Biomphalaria pfeifferi (Gastropoda, Planorbidae). J Molluscan Stud 1990, 56:383-391.
    • 39. Campbell G, Noble LR, Rollinson D, Southgate VR, Webster JP, Jones CS: Low genetic diversity in a snail intermediate host (Biomphalaria pfeifferi Krass, 1848) and schistosomiasis transmission in the Senegal River Basin. Mol Ecol 2010, 19:241-256.
    • 40. Davies CM, Webster JP, Kruger O, Munatsi A, Ndamba J, Woolhouse MEJ: Host-parasite population genetics: a cross-sectional comparison of Bulinus globosus and Schistosoma haematobium. Parasitology 1999, 119:295-302.
  • Inferred research data

    The results below are discovered through our pilot algorithms. Let us know how we are doing!

    Title Trust
    73
    73%
  • Discovered through pilot similarity algorithms. Send us your feedback.

Share - Bookmark

Cite this article