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Macedo, Maíra Bidart; Groll, Andrea Von; Fissette, Krista; Palomino, Juan Carlos; da Silva, Pedro Eduardo Almeida; Martin, Anandi (2012)
Publisher: Sociedade Brasileira de Microbiologia
Journal: Brazilian Journal of Microbiology
Languages: English
Types: Article
Subjects: Medical Microbiology, nitrate reductase assay, tuberculosis, Microbiology, QR1-502, Short Communication, multidrug resistant, sodium nitrate, multidrug resistant, sodium nitrate
We validated the nitrate reductase assay (NRA) for the detection of multidrug-resistant Mycobacterium tuberculosis (MDR-TB) using sodium nitrate (NaNO3) in replacement of potassium nitrate (KNO3) as nitrate source. NaNO3 is cheaper than KNO3 and has no restriction on use which facilitates the implementation of NRA to detect MDR-TB.