LOGIN TO YOUR ACCOUNT

Username
Password
Remember Me
Or use your Academic/Social account:

CREATE AN ACCOUNT

Or use your Academic/Social account:

Congratulations!

You have just completed your registration at OpenAire.

Before you can login to the site, you will need to activate your account. An e-mail will be sent to you with the proper instructions.

Important!

Please note that this site is currently undergoing Beta testing.
Any new content you create is not guaranteed to be present to the final version of the site upon release.

Thank you for your patience,
OpenAire Dev Team.

Close This Message

CREATE AN ACCOUNT

Name:
Username:
Password:
Verify Password:
E-mail:
Verify E-mail:
*All Fields Are Required.
Please Verify You Are Human:
fbtwitterlinkedinvimeoflicker grey 14rssslideshare1
Webster, BL; Diaw, OT; Seye, MM; Webster, JP; Rollinson, D (2013)
Publisher: Public Library of Science (PLoS)
Journal: PLoS Neglected Tropical Diseases
Types: Article
Subjects: RC955-962, Research Article, Biology, RA1-1270, Public aspects of medicine, Arctic medicine. Tropical medicine, Zoology, Parasitology

Classified by OpenAIRE into

mesheuropmc: parasitic diseases
BACKGROUND: Schistosomes are dioecious parasitic flatworms, which live in the vasculature of their mammalian definitive hosts. They are the causative agent of schistosomiasis, a disease of considerable medical and veterinary importance in tropical and subtropical regions. Schistosomes undergo a sexual reproductive stage within their mammalian host enabling interactions between different species, which may result in hybridization if the species involved are phylogenetically close. In Senegal, three closely related species in the Schistosoma haematobium group are endemic: S. haematobium, which causes urogenital schistosomiasis in humans, and S. bovis and S. curassoni, which cause intestinal schistosomiasis in cows, sheep and goats. METHODOLOGY/PRINCIPAL FINDINGS: Large-scale multi-loci molecular analysis of parasite samples collected from children and domestic livestock across Senegal revealed that interactions and hybridization were taking place between all three species. Evidence of hybridization between S. haematobium/S. curassoni and S. haematobium/S. bovis was commonly found in children from across Senegal, with 88% of the children surveyed in areas of suspected species overlap excreting hybrid miracidia. No S. haematobium worms or hybrids thereof were found in ruminants, although S. bovis and S. curassoni hybrid worms were found in cows. Complementary experimental mixed species infections in laboratory rodents confirmed that males and females of each species readily pair and produce viable hybrid offspring. CONCLUSIONS/SIGNIFICANCE: THESE DATA PROVIDE INDISPUTABLE EVIDENCE FOR: the high occurrence of bidirectional hybridization between these Schistosoma species; the first conclusive evidence for the natural hybridisation between S. haematobium and S. curassoni; and demonstrate that the transmission of the different species and their hybrids appears focal. Hybridization between schistosomes has been known to influence the disease epidemiology and enhance phenotypic characteristics affecting transmission, morbidity and drug sensitivity. Therefore, understanding and monitoring such inter-species interactions will be essential for optimizing and evaluating control strategies across such potential hybrid zones.
  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

    • 1. Arnold M (1997) Natural Hybridization and Evolution. Oxford: Oxford University Press.
    • 2. Mallet J (2005) Hybridization as an invasion of the genome. Trends Ecol Evol 20: 229-237.
    • 3. Dowling TE, DeMarais BD (1993) Evolutionary significance of introgressive hybridization in cyprinid fishes. Nature 362: 444-446.
    • 4. Grant PR, Grant BR (1992) Hybridization of bird species. Science 256: 193- 197.
    • 5. Johnston JA, Arnold ML, Donovan LA (2003) High hybrid fitness at seed and seedling life history stages in Louisiana Irises. J Ecol 91: 438-446.
    • 6. Rieseberg LH, Raymond O, Rosenthal DM, Lai Z, Livingstone K, et al. (2003) Major ecological transitions in wild sunflowers facilitated by hybridization. Science 301: 1211-1216.
    • 7. Arnold ML (2004) Natural hybridization and the evolution of domesticated, pest and disease organisms. Mol Ecol 13: 997-1007.
    • 8. Machado CA, Ayala FJ (2001) Nucleotide sequences provide evidence of genetic exchange among distantly related lineages of Trypanosoma cruzi. Proc Natl Acad Sci U S A 98: 7396-7401.
    • 9. Seehausen O (2004) Hybridization and adaptive radiation. Trends Ecol Evol 19: 198-207.
    • 10. Barton NH (2001) The role of hybridization in evolution. Mol Ecol 10: 551- 568.
    • 11. Tsai H-F, Liu J-S, Staben C, Christensen MJ, Latch GC, et al. (1994) Evolutionary diversification of fungal endophytes of tall fescue grass by hybridization with Epichloe¨ species. Proc Natl Acad Sci U S A 91: 2542-2546.
    • 12. Mavarez J, Salazar CA, Bermingham E, Salcedo C, Jiggins CD, et al. (2006) Speciation by hybridization in Heliconius butterflies. Nature 441: 868-871.
    • 13. Detwiler JT, Criscione CD (2010) An infectious topic in reticulate evolution: Introgression and hybridization in animal parasites. Genes 1: 102-123.
    • 14. Brasier CM, Cooke DEL, Duncan JM (1999) Origin of a new Phytophthora pathogen through interspecific hybridization. Proc Natl Acad Sci U S A 96: 5878-5883.
    • 15. WHO (2010) World Health Organisation. Schistosomiasis, Fact Sheet No 115.
    • 16. De Bont J, Vercruysse J (1997) The epidemiology and control of cattle schistosomiasis. Parasitol Today 13: 255-62.
    • 17. Taylor M (1970) Hybridization experiments on five species of African schistosomes. J Helminth 44: 253-314.
    • 18. Southgate VR, Rollinson D, Ross GC, Knowles RJ (1982) Mating-behavior in mixed infections of Schistosoma haematobium and Schistosoma intercalatum. J Nat Hist 16: 491-496.
    • 19. Webster BL (2003) On the interactions of Schistosoma haematobium, S. guineensis and their hybrids in the laboratory and in the field. PhD Thesis. London: University College London.
    • 20. Wright CA, Ross GC (1980) Hybrids between Schistosoma haematobium and S. mattheei and their identification by isoelectric-focusing of enzymes. Trans R Soc Trop Med Hyg 74: 326-332.
    • 21. Kruger FJ, Hamilton-Attwell VL, Schutte CHJ (1986a) Scanning electron microscopy of the teguments of males from five populations of Schistosoma mattheei. Onderstepoort J Vet Res 53: 109-110.
    • 22. Kruger FJ, Schutte CHJ, Visser PS, Evans AC (1986b) Phenotypic differences in Schistosoma mattheei ova from populations sympatric and allopatric to S. haematobium. Onderstepoort J Vet Res 53: 103-107.
    • 23. Pitchford RJ (1959) Cattle schistosomiasis in man in the Eastern Transvaal. Trans R Soc Trop Med Hyg 53: 285-290.
    • 24. Pitchford RJ (1959) Observations of a possible hybrid between two schistosomes, S. haematobium and S. mattheei. Trans R Soc Trop Med Hyg 55: 44-51.
    • 25. Burchard TD, Kern P (1985) Probable hybridisation between S. intercalatum and S. haematobium in Western Gabon. Trop Geo Med 37: 119-123.
    • 26. Wright CA, SouthgateVR, Vanwijk HB, Moore PJ (1974) Hybrids between Schistosoma haematobium and Schistosoma intercalatum in Cameroon. Trans R Soc Trop Med Hyg 68: 413-414.
    • 27. Morgan JAT, DeJong RJ, Lwambo NJS, Mungai BN, Mkoji GM, et al. (2003) First report of a natural hybrid between Schistosoma mansoni and S. rodhaini. J Parasitol 89: 416-418.
    • 28. Steinauer ML, Hanelt B, Mwangi IN, Maina GM, Agola LE, et al. (2008) Introgressive hybridization of human and rodent schistosome parasites in western Kenya. Mol Ecol 17: 5062-5074.
    • 29. Mone´ H, Minguez S, Ibikounle´ M, Allienne JF, Massougbodji A, et al. (2012) Natural Interactions between S. haematobium and S. guineensis in the Republic of Benin. The Scientific World Journal: doi:10.1100/2012/793420.
    • 30. Shrivastava J, Qian BZ, McVean G, Webster JP (2005) An insight into the genetic variation of Schistosoma japonicum in mainland China using DNA microsatellite markers. Mol Ecol 14: 839-849.
    • 31. Gower CM, Shrivastava J, Lamberton PHL, Rollinson D, Webster BL, et al. (2007) Development and application of an ethically and epidemiologically advantageous assay for the multi-locus microsatellite analysis of Schistosoma mansoni. Parasitology 134: 523-536.
    • 32. Huyse T, Webster BL, Geldof S, Stothard JR, Diaw OT, et al. (2009) Bidirectional introgressive hybridisation between a cattle and human schistosome species. Plos Pathog 5: e1000571.
    • 33. Webster BL (2009) Isolation and preservation of schistosome eggs and larvae in RNAlater facilitates genetic profiling of individuals. Parasit Vectors 2: 50.
    • 34. Steinauer ML, Blouin MS, Criscione CD (2010) Applying evolutionary genetics to schistosome epidemiology. Infect Genet Evol 10: 433-443.
    • 35. Tchuem Tchuente´ LA, Morand S, ImbertEstablet D, Delay B, Jourdane J (1996) Competitive exclusion in human schistosomes: The restricted distribution of Schistosoma intercalatum. Parasitology 113: 129-136.
    • 36. Tchuem Tchuente´ LA, Southgate VR, Njiokou F, Njine T, Kouemeni LE, et al. (1997) The evolution of schistosomiasis at Loum, Cameroon: replacement of Schistosoma intercalatum by S. haematobium through introgressive hybridization. Trans R Soc Trop Med Hyg 91: 664-665.
    • 37. Webster BL, Tchuente LAT, Southgate VR (2007) A single-strand conformation polymorphism (SSCP) approach for investigating genetic interactions of Schistosoma haematobium and Schistosoma guineensis in Loum, Cameroon. Parisitol Res 100: 739-745.
    • 38. Webster BL, Southgate VR, Littlewood DTL (2006) A revision of the interrelationships of Schistosoma including the recently described Schistosoma guineensis. Int J Parasitol 36: 947-955.
    • 39. Vercruysse J, Southgate VR, Rollinson D (1985) The epidemiology of human and animal schistosomiasis in the Senegal River Basin. Acta Trop 42: 249-59.
    • 40. Vercruysse J, Southgate VR, Rollinson D, De Clercq D, Sacko M, et al. (1994) Studies on transmission and schistosome interactions in Senegal, Mali and Zambia. Trop Geogr Med 46: 220-226.
    • 41. Rollinson D, Southgate VR, Vercruysse J, Moore PJ (1990) Observations on natural and experimental interactions between Schistosoma bovis and Schistosoma curassoni from West-Africa. Acta Trop 47: 101-114.
    • 42. Bremond P, Sellin B, Sellin E, Nameoua B, Labbo R, et al. (1993) Evidence for the introgression of the human parasite Schistosoma haematobium by genes from Schistosoma bovis, in Niger. Comptes Rendus De L'Academie Des Sciences Serie Iii-Sciences De La Vie-Life Sciences 316: 667-670.
    • 43. Rollinson D, Simpson AJG (1987) The biology of schistosomes. From genes to latrines. London: Academic Press Ltd.
    • 44. Rollinson D, Vercruysse J, Southgate VR, Moore PJ, Ross GC, et al. (1987). Observations on human and animal schistosomiasis in Senegal. In: Geerts S, Kumar V, Brandt J, editors. Helminth Zoonoses. Martinus Nijhoff Publishers. pp. 119-131.
    • 45. Pitchford RJ, Visser PS (1975) A simple and rapid technique for quantitative estimation of helminth eggs in human and animal excreta with special reference to Schistosoma sp. Transactions R Soc trop Med Hyg 69: 318-322.
    • 46. Webster BL, Rollinson D, Stothard JR, Huyse T (2009) Rapid diagnostic multiplex PCR (RD-PCR) to discriminate Schistosoma haematobium and S. bovis. J Helminthol 84: 107-14.
    • 47. Sang T, Crawford DJ, Stuessy TF (1995) Documentation of reticulate evolution in Peonies (Peonia) using internal transcribed spacer sequences of nuclear ribosomal DNA - implications for biogeography and concerted evolution. Proc Natl Acad Sci U S A 92: 6813-6817.
    • 48. Aguilar JF, Rossello JA, Feliner GN (1999) Nuclear ribosomal DNA (nrDNA) concerted evolution in natural and artificial hybrids of Armeria (Plumbaginaceae). Mol Ecol 8: 1341-1346.
    • 49. Dover GA (1986) Molecular drive in multigene families - how biological novelties arise, spread and are assimilated. Trends in Genetics 2: 159-165.
    • 50. De Bont J, Vercruysse J, Southgate VR, Rollinson D, Kaukas A (1994) Cattle schistosomiasis in Zambia. J Helminth 68: 295-299.
    • 51. Duplantier JM, Sene M (2000) Rodents as reservoir hosts in the transmission of Schistosoma mansoni in Richard Toll, Senegal, West Africa. J Helminth 74: 129- 135.
    • 52. McGarvey ST, Zhou XN, Willingham AL, Feng Z, Olveda R (1999) The epidemiology and host-parasite relationships of Schistosoma japonicum in definitive hosts. Parasitol Today 15: 214-215.
    • 53. Riley S, Carabin H, Belisle P, Joseph L, Tallo V, et al. (2008) Multi-host transmission dynamics of Schistosoma japonicum in Samar Province, the Philippines. Plos Medicine 5: 70-78.
    • 54. Southgate VR, Rollinson D, Ross GC, Knowles RJ, Vercruysse J (1985). On Schistosoma curassoni, S. haematobium and S. bovis from Senegal: development in Mesocricetus auratus, compatibility with species of Bulinus and their enzymes. J Nat Hist 19: 1249-1267.
    • 55. Vercruysse J, Southgate VR, Rollinson D, Hilderson H (1989) Experimental chemotherapy of Schistosoma curassoni in mice. Para Res 75: 559-562
    • 56. Monrad J, So¨ re´n K, Johansen MV, Lindberg R, Ornbjerg N (2006) Treatment efficacy and regulatory host responses in chronic experimental Schistosoma bovis infections in goats. Parasitology 133: 151-158.
    • 57. Pitchford RJ, Lewis M (1978) Oxamniquine in treatment of various schistosome infections in South-Africa. South African Medical Journal 53: 677-680.
  • Discovered through pilot similarity algorithms. Send us your feedback.