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Tanneberger, Amelie (2012)
Publisher: Freie Universität Berlin Universitätsbibliothek, Garystr. 39, 14195 Berlin
Languages: German
Types: Doctoral thesis
Subjects: 610 Medizin und Gesundheit, 610 Medical sciences; Medicine, ultrasonography, lymphedema, lipedema
ddc: ddc:610

Classified by OpenAIRE into

mesheuropmc: body regions
Introduction We determined the skin thickness of the legs in seventeen healthy subjects and 71 patients with lymph- and lipedema using 20 MHz ultrasonography. The aim was to find out, whether there are any differences in skin thickness in patients with lymph- and lipedema as compared to the healthy subjects. Methods From August 2007 until April 2008 we investigated 71 patients with swelling of the legs due to different causes. The study included patients with primary lymphedema, secondary lymphedema and lipedema. At 12 points on the legs the skin thickness was measured and compared to a control group containing patients without leg swelling. Results In primary (p<0,0005) and secondary (p=0,008) chronic lymphedema, ultrasonography revealed a statistically significant increase of skin thickness as compared to the healthy subjects. In lipedema (p=0,539) a statistically significant increase of skin thickness compared to the healthy subjects could not be shown. The influence of BMI and age on skin thickness was not significant in any of the groups. Conclusion The measurement of skin thickness using sonography in patients with swelling of the legs can be useful to objectify the severity of the leg swelling in addition to the clinical examination. In the future the method could be useful to evaluate therapy and to objectify the progress of the disease.
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