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D. V. Nebieridze (2007)
Publisher: Stolichnaya Izdatelskaya Kompaniya
Journal: Racionalʹnaâ Farmakoterapiâ v Kardiologii
Languages: English
Types: Article
Subjects: RC666-701, diltiazem, RM1-950, антагонисты кальция, дисфункция эндотелия, Therapeutics. Pharmacology, endothelium dysfunction, Diseases of the circulatory (Cardiovascular) system, дилтиазем, calcium antagonists

The efficacy of calcium antagonists widely used in cardiological practice is proved both by placebo-controlled studies and in comparative trials with end-point control. Calcium antagonists are the most effective vasoprotective medicines. In our study we had shown antihypertensive efficacy and ability to improve endothelium function of non-dihydropyridine calcium antagonist, diltiazem (Altiazem RR). Altiazem RR can be drug of choice in wide profile of patients with arterial hypertension, especially in those with concomitant metabolic abnormalities, diabetes mellitus and ischemic heart disease.

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