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fbtwitterlinkedinvimeoflicker grey 14rssslideshare1
Fukami, M H; Haavik, J; Flatmark, T (1990)
Languages: English
Types: Article
Subjects: Research Article

Classified by OpenAIRE into

mesheuropmc: endocrine system
Identifiers:pmc:PMC1131466
Incubation of bovine chromaffin cells with L-[14C]phenylalanine resulted in label accumulation in catecholamines at about 30% of the rate seen with L-tyrosine as precursor. Studies with purified tyrosine hydroxylase (EC 1.14.16.2) showed that the enzyme catalysed the hydroxylation of L-phenylalanine first to L-p-tyrosine and then to 3,4-dihydroxyphenylalanine (DOPA). No evidence for a significant involvement of an L-m-tyrosine intermediate in DOPA formation was found.
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