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Yandow, Suzanne M.; Rimoin, David L.; Grace, Aimee M.; Fillman, Ramona R.; Raney, Ellen M. (2009)
Languages: English
Types: Article
Subjects: Article

Classified by OpenAIRE into

mesheuropmc: integumentary system, congenital, hereditary, and neonatal diseases and abnormalities, nutritional and metabolic diseases
Identifiers:pmc:PMC2841562
Treating patients with Hutchinson-Gilford progeria syndrome (HGPS) are based on the abnormalities of accelerated aging that affect the healing processes, combined with a fragile cardiovascular status. A classic HGPS case is presented, of Korean ancestry, who was treated for severe coxa valga with bilateral varus osteotomies using blade plate fixation. Complications over the blade plate area required removal of the hardware, after which the patient displayed left-sided hypertonicity--determined to be a cerebrovascular accident. Subsequently, she returned almost completely to her pre-surgical neurologic status. Perioperative planning for HGPS patients should include risks typically considered in the planning for geriatric patient care.
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