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Dmytryshyn, B. Ya. (2015)
Publisher: Ivano-Frankivsk National Medical University
Journal: Galician Medical Journal
Languages: English
Types: Article
Subjects: children; acute obstructive bronchitis; immunoglobulins; disease prognosis
The research involved examination of 36 children at the age from 3 months to 3 years with acute obstructive bronchitis and 30 children with acute nonobstructive bronchitis. During the research, the clinical method, chest radiography and immunological method were applied. All children with acute obstructive bronchitis were treated with oral rehydration, ambroxol orally, salbutamol, budesonide in the form of an aerosol dosed with a spacer or nebulation in respective age-dependent doses.In the vast majority of children (64.1%) the acute obstructive bronchitis first occurred in the first half of their life. Family history of allergies was burdened in 91.6% of children and 47.2% of children had their own allergic anamnesis. Breastfeeding was received by 30.6% of children, mixed feeding was received by 33.3%, 36.1% of children received artificial feeding. On admission of patients with acute obstructive bronchitis they were characterized with the following signs: intoxication syndrome (72.2%), colliquative unproductive cough (75.0%), moderate expiratory dyspnea (77.8%), box sound during chest percussion, harsh breathing with dry and bubbling rales during auscultation (91.7%). Radiological test defined the following: increase in bronchopulmonary markings and hypo-pneumatization areas in the lateral sections. In the blood there was determined the following: eosinophilia (47.2% of patients) and aneosinophilia (13.9%); IgG and IgA reduction in serum, IgE increased content in children with acute obstructive bronchitis.After the treatment undergone by the children with acute obstructive bronchitis, the cough remained clinically up to 9 days; dyspnea remained for 1.5 days, physical phenomena above the lungs – for 3 days. During the study of the immune status, the level of IgG and IgA rose slightly though IgE slightly decreased in children in both study groups, but it remained significantly increased if compared to the indices of healthy children. The provided treatment did not contribute to any significant adjustments of the immune status parameters of patients, though there was only a tendency to their normalization, while in the children with acute bronchitis it was dynamic.
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